Professor Liu Runxia Infertility Treatment Of Polycystic Ovary Syndrome's Academic Thoughts And Clinical Experience In The Research

Objective:polycystic ovarian syndrome (PCOS) is a kind of endocrine syndrome with much cause and clinical polymorphism.its clinical principal features is too much androgen and continuous no ovulation,which is one of the causes of reproductive age women menstrual disorders and infertility.professor Liu Runxia,the fourth group of an old Chinese medicine academic experience inheritance work guiding teacher. she is good at diagnosis and treatment of infertility. she proposed her own original ideas for PCOS of principle, method, square and medicine,and accumulated the rich experience on governance,formed their own expertise and characteristic. This artiele summary comprehensivly and systematieally on advisor’academie experience in treatment of infertility with polycystic ovarian syndrome.Method:two methods of the theory research and clinical study will be put to use in system summary the academic experience about the treatment of PCOS infertility. On theory research, mainly through investigate the classical literature, combine the recognition of classical theory, analysis, induce past dynasties doctors’s cognition about infertility with Polycystic Ovary Syndrome. Combine modern research results on Polycystic ovary syndrome with infertility.to research wiewpoit and characteristics of reasonand law,power and medicine of Professor Liu Runxia on Polycystic Ovary Syndrome infertility, comprehensively summed up the views of academic thought and clinical experiences,to analyze the ideological origins of academic.On clinical research,use the tiaojing zhuyun Recipe for clinical treatment study, wich is Professor Liu Runxia experience in treating infertility of PCOS.sixty cases of PCOS randomly divided into groups of traditional Chinese medicine (tiaojing zhuyun Recipe), the Western Group (letrozole) and Chinese and Western medicine group (tiaojing zhuyun Recipe and letrozole), each set of twenty patients each,three menstrual cycles for a course, two courses were observed. Clinical syndromes, restore ovulation, pregnancy rate, levels of and serum sex hormone (E2、FSH、LH、P、T、T), anti-paramesonephricduct hormone (AMH),are observed before and after treatment, follicular development and ovulation, ovary, follicular walls, uterine blood flow parameters impact.Permits the analysis of clinical efficacy and its possible mechanism.Results:On theory, The fist of the aeademic thinking of Professor Liurunxia is discuss and treating menses disease and infertility with liver,spleen and kidney centre, paying attention to supplement kidney marrow,adjust the liver and the spleen.The second is basis on the gas and blood,disputting the deficient or stagnate of qi and blood,attaching importance to regulating the qi and live the blood.The thid is regulation and supplement of Tiangui as gynaecology in common use way. The fourth is advocting preventive treatment of disease. The fifth is using two period therapy compled with therhythm of menses.The sixth is using medicine like resort to arms,direction selection is precise and appropriate,forming prescription based on high frequency medicine reported by research and the dose is moderate.There are four origin of her academic thinking.First,Absorb the essence of the classic medical books.Second,ancient physicians recognized for liver and infertility.Third,Reference to the academic point of view about contemporary physicians on the liver with PCOS irregular menstruation,and infertility. Fourth,Combined with modern medical research developments.Professor Liu Runxia considered that the cause of polycystic ovary syndrome is relate to the natural endowment and acquired factors.the natural endowment is the basis of pathogenesis, improper diet,emotional upset occurrence is an important factor. Renal dysfunction of liver and spleen is the main pathogenesis.Stagnation, phlegm, blood stasis causing wet tiangui disorders is the main pathology. liver, spleen, kidney disease management interaction, gas, phlegm, blood stasis into each other, resulting in staggered complex pathogenesis.But the pathogenesis of liver Qi stagnation is the hub. Disease resistance-based virtual reality.Stagnation of liver, spleen and kidney deficiency.qi stagnation, blood stasis, phlegm as the standard. Actual situation mixed syndromes, clinical polymorphism, and cured. In terms of clinical thinking, advocate disease prevention, emphasizing the prevention is more important than cure. To adjust the physical conditioning, pay attention to diagnosis and treatment of menstruation in adolescence as a preventive measure. Stagnation of phlegm-dampness Constitution and the Constitution is the two most significant physical signs in patients with PCOS.The pathogenesis of PCOS through puberty at high risk for Chinese tone body differentiation.Can effectively control the occurrence and development of PCOS infertility prevention. In the diagnosis and treatment aspects, PCOS disease complex, diverse symptoms.Mentor advocates identified disease, identified the body and syndromes combined, the combination of macro and micro.Expanded clinical observations and meticulous, and lay the Foundation for the right argument.And severity of the disease and treatment effect to do scientific and objective judgement. Based on understanding of the pathogenesis of the disease, which establish the symptoms, treatment principles of reinforcement and elimination in combination. she advocates liver, spleen and kidney, pays attention to replenish kidney essence, regulating liver-Qi.Qi and phlegm and blood stasis and energy dissipation, Qi, resolving phlegm and removing blood stasis.Formed the kidney and fine, ShuGan the spleen, eliminating phlegm to invigorate the treatment method.Founded the treatment of PCOS basic recipe-menstruation progesterone side.Consists of placenta hominis, antler glue, epimedium, Dodder seed, Ligustrum, ink dry Lotus and rhizoma pinelliae,(biliary) South star, Radix rehmanniae, Angelica sinensis, Radix paeoniae Alba, peach seed, safflower, Cyperus and so on. When applying tiaojing treatment based on syndrome differentiation Treating. PCOS divides into the two types. Obesity, mostly of spleen and kidney-Yang deficiency and phlegm stagnation.Non-obese (body lean) model, mostly in liver and kidney, blood stasis.Clinical experience think polycystic ovarian syndrome infertility duty to regulate the menstrual function, help pregnant and Ann tire.the seed must first menstruation" Regulation of the menstrual cycle is the focus of mentor infertility treatment of PCOS.Conditioning Tiangui, is the basic method of menstruation. Instructors to promote ovarian follicle and discharge as the key to treatment of PCOS Infertility. Promote ovulation fill aquiculture blood yiqi, help follicular.Qi and phlegm and blood circulation, follicle-stimulating discharge. If patients become pregnant, solid red kidney, nourishing tocolysis to promote fetal growth and development of effective methods. For complex disease, the course is longer.Because it can not persist long-term use of traditional Chinese medicine and patients eager to pregnancy.used the method of combining traditional Chinese and western medicine, take advantage of each other, improve the clinical effect. Promote physical and mental wen, made that good wins medicine.Clinical trial results suggest that Chinese and Western medicine group in ovulation rate and pregnancy rate are higher than Chinese medicine and western medicine group (P<0.05).In the serum T, LH, AMH decreased compared with before treatment.Chinese and Western medicine group was statistically significanter than the Western medicine group (P<0.05).It was not statistically significanter than Chinese medicine group (P>0.05). E2and P lever after treatment was higher than before treatment in each group, and was statistically significant. Chinese and Western medicine group was statistically significanter than the Western medicine group (P <0.05),but was not statistically significanter than Chinese medicine group (P>0.05).Follicle wall artery, uterine blood flow PSV, EDV were higher and RI lower after treatment than before treatment in each group, and was statistically significant (P <0.05).Conclusion:Professor Liu runxia has read carefully over and over all kinds of classic of TCM,respect ancient but don’t obstinately follow tradition.blogmark the advantage of all doctor, achieve mastery through a comprehensive,heart chanese and refer western,academically bothand,has got at absorting essence of various medical expert. The theory,method, parties and drugs for treatmenting of polycystic ovary syndrome has certain characteristics.Emphasis on the fuction of liver,kidney and spleen in the etiology and pathogenesis of this disease. The fundamental treatment law was replenishing kidney essence and soothing liver and strengthening spleen, invigorate the circulation of blood and reduce phlegm.The comprehensive treatment method was grading and circumference combine with dialection.It has a great role of Diagnosis and treatment of PCOS infertility.lt is worth further study, mining and systems analysis.We have to innovate on the basis of inheritance.Tiaojing zhuyun Recipe has a good effect in patients with PCOS infertility.It can improve the clinical syndrome, to promote ovulation and improve the pregnancy rate.Mechanism may be related to menstruation progesterone side to adjust the PCOS patients with disorders of sex hormone infertility level, regulation of ovarian blood flow, improve the follicle wall and the uterine blood flow.