Syndrome Differentiation And Treatment Law Of Chronic Heart Failure Based On Complex Network Technology

Objective:To investigate syndrome differentiation and treatment laws of the chronic heart failure.Methods:Use method of retrospective survey to collect CHF clinical data of three chinese medicine hospital in the past five years, including1840cases of CHF hospitalized patients, and build complex network diagram of syndrome differentiation and treatment laws, calculate the node degree distribution, investigate syndrome differentiation and treatment laws of the chronic heart failure.Results:CHF syndrome-treatment with drugs node degree distribution-ho rate characteristics, with core structure. The core organizational structure of scale-free networks: the core treatment method is benefiting qi, warming Yang, activating blood circulation, diuresis, invigorating the spleen, regulating qi-flowing, eliminating phlegm, dispersing liver; core drugs:Poria, Atractylodes, Cinnamon Twig, Astragalus, Licorice root, Alisma, Motherwort, Dried tangerine peel, Bupleurum root, Turmeric, Red sage root, Chinese angelica, Radix, Fructus Aurantii, Pinellia tuber, Pepperweed seed, Maodongqing;closely associated syndrome:invigorating spleen, benefiting qi, diuresis, dispersing liver, regulating qi-flowing, eliminating phlegm, activating blood circulation, warming yang, clearing heat, nourishing yin (according to the associated degree in descending order).Conclusion:CHF card to laws that have a scale-free network characteristics, there are common core structure. According to "to the medicine syndrome" reverse inference model, the core of chronic heart failure syndrome is Yang deficiency of both qi, blood stasis water stop; The temperature Yang, promoting blood circulation:the water is its core treatment; The spleen, eliminating phlegm ShuGan qi in the network correlation degree is higher, spleen, stomach phlegm obstruction and chronic heart failure should be the important syndrome, different from previous research. The complex network technology for traditional chinese medicine research disease can provide the expected but valuable implicit information, and then the pattern identification and treatment for clinical provides an objective basis.