Gastric cancer is the most common malignant tumor in China. So it will be crucial not only for understanding the molecular mechanisms underlying development and progression, but also for finding a putative biomarker of tumor prognosis and for formulating more effective therapeutic targets. We used DNA microarray to analysize gene expression differences between gastric cancer and normal tissues, and after the confirmation of PCR&WB, we selected SLC38A1 as the interested gene. And we used tissue microarray blocks containing gastric cancer tissue and matched noncancer gastric tissue specimens and in vitro studies to detect the expression of SLC38A1 in Chinese patients with gastric cancer and its clinical effects; We also performed some experiments to explore the underlying mechanisms.
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