Clinical Research Of Points Catgut Embedding Plus Acupuncture For Nerve Root Sciacca

ObjectiveTo observe the clinical effectiveness and safety of points catgut embedding combining with acupuncture for nerve root Sciatica and to evaluated abjectly the therapeutic effect, the study adapted the clinical randomized-controlled trial, by using clinical epidemiology,methodology of clinical science and statistics method. Through this study, further standardization clinical effectiveness and better social effect could be obtained.MethodsAll cases were recruited from Taiwan Liu Keyou Chinese Medicine Clinic from April,2009 to March,2010. Eighty patients with Sciatic who met the criteria were randomly divided 1:1 into the treatment group (Acupoint Thread Embed plus acupuncture) and the control group (acupuncture only). All cases received treatment once two days for five times as one course. VAS score,BRS-6 behavior score,MG-Gill pain Scoreboard were used to evaluate the treatment effect and safety test, and clinical effectiveness was judged by the industry standards of Traditional Chinese Medicine in China, which named Effectiveness Standard of Diseases and Syndrome Diagnosis in Traditional Chinese Medicine EPIDATA3.1 software was used to establish database, and SPSS15.0 was applied to make statistics analysis. Measurement data was expressed by mean±standard deviation (χ±S), and count data was showed by constituent ratio(%). Measurement data was analyzed by t test (if variance arrhythmias existed, data would be analyzed by t'test or Rank sum test); before and after self-cooperation was handled by t test or Wilcoxon Paired Rank Sum Test. Categorical data using Chi-Square test, ranked data using two-samples compared Wilcoxon rank sum test (adjusted).Statistical graphic manufacture was finished by Graph Pad Prism 4.03 software.ResultsEighty cases were recruited totally from outpatient department. Among them, there were thirty nine men and forty one women, aged between 31-58, with course of disease between one month and twenty four months. There were forty cases (sixteen men and twenty four women) in the treatment group and forty cases (twenty three men and seventeen women) in the control group, with the average age of 47.89 years and 45.12 years relatively and the average course of disease of the patients in two groups was 10.37 months and 9.73 months relatively. In two groups, the baseline that including gender,age,course of disease,pain degree,syndrome differentiation type,PRI cognition,PRI emotion,PRI total score,VAS score,pain severity,behavior pain (BRS-6) score was no significance of differences statically, which suggested baseline data in two groups could be comparable.Comparison of pain condition:after one treatment course, sore of PRI cognition,PRI emotion,PRI total score,VAS score,pain severity,behavior pain (BRS-6) reduced in both groups, with significant difference statistically (P<0.05),which indicated scale score used above could be lowered and pain symptom could be released and quality of life be improved in two groups. By group comparison, sore of PRI cognition,PRI emotion,PRI total score,VAS score,pain severity,behavior pain (BRS-6) reduced more significantly in treatment group (P<0.05),which suggested the effect of points catgut embedding plus acupuncture treating nerve root Sciacca be significant.After treatment, pain severity of all cases was ease more or less in both groups and the severity of serious pain patients turned to moderate,light or even disappear. Especially in the treatment group, pain degree of 80% patients was under light degree and pain of 37.5% patients disappeared, which showed significant efficacy. Yet pain degree of 60% patients was under light degree. The comparison of pain severity in two groups was different significantly (P<0.05).Therapeutic effect comparison:after one therapeutic course, in the treatment group,22 cases were sanative,16 cases became better,2 cases failed to improve, and the total effective rate was 95.0%; and in the control group, 10 cases,22 cases,8 cases and 80.0% relatively. Compared with two groups, both the clinical efficacy and total effective rate showed significant difference (P<0.05). The treatment group made better in the total effective rate (95.0% compared with 80.0%), which indicated points catgut embedding plus acupuncture could firmly treat nerve root Sciacca. Before and after treatment, the blood routine,urine routine,stool routine,liver and renal function,electrocardiogram were tested. All the results showed no abnormal, which indicated therapy of points catgut embedding combining with acupuncture could be safe,effective and no adverse effect.ConclusionJudging from all the clinical results mentioned above, points catgut embedding plus acupuncture to treat nerve root Sciacca of nerve roots could be convenient and economical, have significant effectiveness and remain safe, which should be applied in clinic.