| OBJECTIVEThe paper analyze and summarize the link between AIDS and the syndrome of Chinese Medicine through the study of theory in order to discuss in TCM.It shows the current research of Chinese Medicine syndrome of AIDS and question.There are two groups of patients.One get infected by paid blood transfusion,the other get infected by intraveneous drug.We get the TCM clinic epidemic data through clinical research and do the statistic research of the morbility mode of the symptoms,objective sign,syndrome correlatin five organs.We get the message of the TCM syndrome rule of the two groups of patients.What's more,we obtain the syndrome essence of AIDS by factor analysis and sum up the TCM syndromes by Clustering analysis.All above set a foundation of the AIDS' TCM syndrome normalization and determination of treatment based in pathogenesis obtained throu-gh differentiation of symptoms and signs.METHOD1.Theory Research:The author read and screened the overall collected domestic AIDS TCM literature,then classified the documents and extract the current useful information about the link between the AIDS and the TCM syndrome and the TCM etiopathogenisis of AIDS and the syndrome of the AIDS.The author chose the representative literature depleting the repeating contents,and extracted all kinds of viewpoint estimating and analyzing objectively. Sorting and comparing the occurrence frequency of the TCM syndrome in statistics.2.Clinical Research:(1) Analyzing the complaint,sign(included tongue appearance and pulse condition), syndrome and invasion of entrails of 170 pieces AIDS patients infected by intraveneous drug in Guang'xi in statistics.Summarizing the syndrome rule and invasion of the entrails.(2) Analyzing the complaint,sign(included tongue appearance and pulse condition), syndrome and invasion of entrails of 297 pieces AIDS patients infected by paid blood-supply in Guang'xi in statistics.Summarizing the syndrome rule and invasion of the entrails.(3) Comparing study about the two groups of patients:complaint,sign(included tongue appearance and pulse condition),syndrome and invasion of entrails.Get the message of the disparity of the two groups.(4) Utilizing SPSS 16.0 to do factor analysis,extracting the AIDS TCM syndrome essence (principal constituent).(5) Utilizing SPSS 16.0 to do Clustering analysis,sorting and summing up the the AIDS TCM syndrome essence. RESULTS1.Comparing study of the complaint,sign.Comparing results of the 73 complaints and signs:occurrence frequency of 57 complains and signs blood-supply infection group is higher than theâ…£drug infection.The most different frequency lies in alopecie.(58.18%) It shows the severity of the pathogenetic condition of the blood-supply group is heavier than theâ…£drug group.The results of the chi-square criterion shows:there are 47 significant deviations or extremely significant deviations(occupied 64.38%) in the occurrence frequency of the complaints and signs,and statistical significance exits.It is thus clear that two groups of the patients' pathogenetic condition are dixtinct.2.Comparing study of syndrome.(1) Sorting syndromes' occurrence frequencyThe higher occurrence frequency in theâ…£drug group in order(exceed 10%):pattern of phlegm-heat congestion of lung,pattern of spleen-stomach qi deficiency,pattern of qi deficiency,pattern of phlegm-moist accumulation in the lung;kidney yin deficiency pattern; heart yin deficiency pattern;pattern of liver depression with qi stagnation;kidney essence insufficiency syndrome;liver yin deficiency pattern;kidney yin and yang deficiency pattern; pattern of liver-stomach disharmony;lung yin deficiency pattern;kidney yang deficiency pattern;pattern of damp-turbidity obstruction.The higher occurrence frequency in the blood-supply group in order:pattern of spleen-stomach qi deficiency;kidney yin and yang deficiency pattern;pattern of liver depression with qi stagnation;pattern of damp-turbidity obstruction;pattern of phlegm-damp congestion of lung;heart qi and yin deficiency pattern;pattern of liver-stomach disharmony; pattern of phlegm-heat congestion of lung;kidney yang deficiency pattern;syndrome of qi stagnation in stomach;heart qi and blood deficiency syndrome;heart qi deficiency pattern; liver yin deficiency syndrome;lung yin deficiency syndrome;kidney yin deficiency syndrome.(2) Comparison of common syndrome occurrence frequencyComparison between two groups in 27 syndromes occurrence frequency:17 syndromes occurrence frequency of the blood-supply group are all higher thanâ…£drug group,the most difference of the occurrence frequency is qi deficiency in spleen-stomach while the little difference of it is lung yin deficiency;occurrence frequency of 10 syndromes inâ…£drug group are higher than them of blood-supply group,the most difference of the occurrence frequency is heart yin deficiency syndrome while the little difference of it is blood deficiency syndrome.The results of the chi-square criterion shows:there is significant deviation or extremely significant deviation of 17 kinds of syndromes in Comparison of common syndrome of two groups,and statistical significance exits.There is extremely significant deviation in 15 syndromes:qi deficiency of spleen-stomach, qi deficiency,kidney yin deficiency,heart yin deficiency,liver depression with qi stagnation, kidney essence deficiency,kidney yin and yang deficiency,disharmony and liver and stomach, pattern of damp-turbidity obstruction,heart qi and yin deficiency,stomach qi stagnation,heart qi deficiency,heart qi and blood deficiency,liver depression with spleen qi deficiency.There are 13 syndromes of P value below 0.001.The syndromes' frequency of blood-supply group is higher of drug group:qi deficiency of spleen-stomach,liver depression with qi stagnation, kidney yin and yang deficiency,disharmony and liver and stomach,pattern of damp-turbidity obstruction,heart qi and yin deficiency,stomach qi stagnation,heart qi deficiency,heart qi and blood deficiency,liver depression with spleen qi deficiency.The occurring frequency of qi deficiency,kidney yin deficiency,heat yin deficiency,kidney essence deficiency,insufficiency of large intestinal fluid syndromes inâ…£drug group are higher than in blood-supply group.3.Multiplicity SyndromeThe syndrome of disharmony of liver and stomach occurs the most inâ…£drug group,and others occurs more(above 5%) are phlegm-heat congestion of lung,kidney yin and yang deficiency syndrome,qi deficiency syndrome,liver depression,pattern of damp-turbidity obstruction,heart yin deficiency syndrome,kidney yin deficiency syndrome,yin deficiency syndrome,all above sophisticates.What's more,qi deficiency syndrome,pattern of damp-turbidity obstruction,liver depression sophisticate.The syndrome pattern of liver depression with spleen qi deficiency and disharmony of liver and stomach occurs the most in blood-supply group,and others occurs more are spleen qi deficiency,kidney yin and yang deficiency,phlegm- damp congestion of lung,pattern of damp-turbidity obstruction,disharmony and liver and stomach,heart qi and blood deficiency, phlegm-heat congestion of lung,heart qi deficiency,stomach qi stagnation,heart qi and yin deficiency,liver yin deficiency,kidney yang deficiency,damp-heat of bladder,all above sophisticates.What's more,kidney yin and yang deficiency,damp-turbidity obstruction,liver depression with spleen qi deficiency,heart qi and yin deficiency,phlegm- heat congestion of lung,stomach qi stagnation,phlegm- damp congestion of lung,disharmony of liver and stomach,liver yin deficiency,heart qi and blood deficiency sophisticate.In addition to,damp-turbidity obstruction and kidney yang deficiency sophisticate.4.Disease Incidence of EntrailsMorbidity of five organs of blood-supply group is higher from 5%to 20%thanâ…£drug group on the face of the incidence of five organs.The results of the chi-square criterion show that morbidity of four organs of two groups is distinct.Liver morbidity has significant deviation(0.030),and it of blood-supply group is higher above 10%thanâ…£drug group.While the morbidity of spleen,heart,kidney are extremely significant deviation,and the value of P is respectively 0.000 spleen,0.000 heart,and 0.000 kidney.All are far less than 1.As a whole entirety pathogenetic condition of blood-supply group is much badly than theâ…£drug group.Kidney yang deficiency syndrome and transformation of liver depression into fire occurrence frequency have significant deviation(P<0.05):kidney yang deficiency syndrome one of deficiency of the blood-supply group is higher than it of theâ…£drug group;syndrome of transformation of liver depression into fire the one of deficiency of theâ…£drug group is higher than it of the blood-supply group.5.Factor Analysis Based on the research above,combined the information of the two groups to a data base, and arranged the complaints and signs 72 variables,and run the process factor analysis. Extracted 21 common factor,referring to the expertise,get the definite AIDS syndrome essence mainly:qi deficiency pattern,spleen deficiency pattern,kidney deficiency pattern, heart deficiency pattern,pattern of liver depression,pattern of phlegm-heat congestion of lung, deficiency-cold pattern(yang deficiency pattern).Furthermore,various kinds complicate complaint combination or single complaint and sign need the accompaniment complaint to analyze by differentiation of symptoms and signs.6.Clustering analysisClustering analysis 72 variable in the data base,fuzzy grouping all the variable into 16 clusters combined expertise.The fraction results of the Clustering analysis are the same with results of the factor analysis.Or the certain common factor added up one or several complaints, signs.The results show:the obvious categorization is kidney deficiency syndrome,heart qi deficiency plus kidney deficiency or blood deficiency,liver depression into fire plus kidney deficiency,stomach qi stagnation,liver-stomach disharmony,deficiency -cold,liver yin deficiency,spleen qi deficiency plus deficiency-heat,phlegm-heat congestion of lung and heart yin deficiency syndrome.In addition to,hidrosis syndrome and stranguria occurs,and or some complex symptoms and signs.Conclusions:1.Overall and systemic searching the domestic data-base and books,do the primary research and summarize the link of the AIDS and Chinese medical science disease and syndromes, etiological factor,syndromes.AIDS is not equal to any kind of Chinese medicine disease and syndromes.However,AIDS' determination of treatment based in pathogenesis obtained through differentiation of symptoms and signs can refer to correlative Chinese disease experience.The current domestic AIDS syndrome research has the following question: nonstandard names,blurry connotation,pedestrian differentiation of symptoms and signs, unreasonable program,and the illegal quality of the syndrome research.2.The complaint,sign,and common syndromes are almost the same inâ…£drug group and blood-supply group.They are commonly:phlegm-heat congestion of lung,phlegm-damp congestion of lung,lung yin deficiency,liver qi stagnation,liver depression into fire,liver yin deficiency,spleen stomach qi deficiency,stomach yin deficiency,stomach qi stagnation, kidney essence deficiency,kidney yang deficiency,kidney yin deficiency,kidney yin and yang deficiency,heart qi deficiency,heart blood deficiency,heart yin deficiency,heart qi and blood deficiency,heart qi and yin deficiency,disharmony of liver and stomach,liver depression and spleen qi deficiency,insufficiency of large intestinal fluid,qi deficiency,and qi and blood deficiency,yang deficiency,blood deficiency,yin and yang deficiency and damp-turbidity obstruction.The comparison results show:the two groups of patients has different frequencies in complaint,sigh,and syndromes.It has significant deviation or extremely significant deviation. The reason may be the contract route,the course of disease length,the mental pressure,the different case collection institute.3.Multiplicity SyndromeThe multiplicity syndrome inâ…£drug group occurs the frequent is the disharmony of liver and stomach,others are phlegm-heat congestion of lung and qi deficiency and 9 syndromes combined.The multiplicity syndrome in blood-supply group occurs the frequent is the liver depression with spleen qi deficiency,disharmony of liver and stomach.Others are spleen and stomach qi deficiency and kidney yin and yang deficiency and 12 syndromes combined.The combined syndromes are not consistent with the traditional five elements clue.They occurs as the link five organs and random combination.4.The results of Factor Analysis and Clustering analysis using professional knowledge: some conclusions links with experiential differentiation of symptoms and signs,using data analysis with no supervising to obtain the AIDS syndrome essence and induction has reference meaning.But its practicability needs to be validate.
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