Chongqing City Population Obesity And Related Diseases, The Relationship Between Survey And Obese Rats, Hypothalamic Leptin Receptor Expression And Significance

Objective To investigate the epidemic status of obesity and its related diseases and to analyze the association of BMI, waist circumference (WC) and waist hip ratio(WHR) with hypertension, hypertriglyceridemia, hyperglycemia and insulin resistance.Methods The questionnaire, body weight, height, blood pressure and other biochemical data were collected.Result The percentage of overweight was 30.93%, obese was 3.51%, abdominal adiposity was 16.27%. The prevalence of obesity was increased with aging. In the whole population investigated, the percentage of hypertension, dislipidemia, hyperglycemia and IR was 34.06%, 45,13%, 27.78%and 7.35%, respectively. With the rise of BMI or WC, the prevalence of these metabolic disorders was also increased. The percentageof upper metabolic disorders was compared using BMI, WC and WHR cut-offs and concluded that abdominal adiposity patients, who were diagnosed with WC-cut-offs, was more likely to suffer from metabolic diseases in men while women could tolerance abdominal adiposity than that of men. With the rise of BMI, the obese subjects were facing the risk of multiple metabolic disorders.Conclusion In the whole population investigated, the prevalence of obese and its related diseases was very high and the obese patients were challenged by multiple metabolic disorders.