Studies On The Mechanisms Of Complex Partial Seizures And Generalized Absence Epilepsy In The Rat

Epilepsy is a common disease which greatly impairs human's health greatly. During recent years, considerable achievement has been made toward the study of epilepsy along with the tremendous advance of neuroscience. Over a long period of time, however, the mechanism of epilepsy has been investigated mainly by the use of electrophysiological and pharmacological methods, and the morphological studies has been limited largely due to the short of efficient morphological tools. Recently, c-fos oncogene expression method, a new morphological method which localizes the neuronal activities at cellular level, emerged as the time require. By exploiting the characteristic rapid increase of c-fos oncogene mRNA and...