Study On Risk Factors Of Essential Hypertension And Coronary Heart Disease For Medical Diagnostic X-ray Workers In China

Radiocarcinogenesis has been the main concerns in the field of radiological protection. Recently, epidemiological studies of the atomic bomb survivors have suggested dose-related increases in mortality from diseases other than cancer. Cardiovascular disease is one such noncancer disease for which increases in both mortality and incidence have been found to be associated with radiation dose. Similar results have been found in several other occupational exposed populations. This include Chinese medical diagnostic x- ray worker's cohort study, which has followed up for over twenty years. From 1980, a nationwide cohort study was carried out on the effects of long-term occupational ionizing radiation. Recent results have indicated that the relative risk of total deathes was 1.20 for the period 1950-1995 and that of cancer was 1.16. However relative risk of the cardiovascular disease was 1.29, and 1.39 for the coronary heart disease. As lack of data about radiation dose and other cardiovascular risk factors, we can't conclude that the increase was a direct effect of ionizing radiation. To further investigate risk factors of cardiovascular diseases, we conducted a nationwide sampling risk factor study, which include prevalence study, case-control study and molecular epidemiology study of essential hypertension and coronary heart disease. The main results manifest as follows: 1. Prevalence study of hypertension and coronary heart diseaseA total of 3949 medical diagnostic X-ray workers were surveyed using multiple stage cluster sampling method. The study subjects come from nearly 400 hospitals across all the country. Diagnosis of essential hypertension and coronary heart disease was according to standard methods and criteria. Comparation of prevalence rate was performed according to the third nationwide sampling survey on essential hypertension.(1) With the increase of age the X-ray worker's blood pressure increases. In the low age period there were no distinct blood pressure difference between X-ray worker and comparative population. In the high age, a statistically different blood pressure was found both for the male and for the female.(2) Blood pressure of X-ray worker was significantly higher than that of other...