Clinical Observation On The Qingtan Ningshen Recipe For The Treatment Of Insomnia With Phlegm-heat Internal Disturbance Syndrom

Objsctive:Guided by the basic theories of traditional Chinese medicine and based on clinical practice,the purpose of this study by observing the clinical efficacy of self-designed Qingtanningshen decotion in the treatment of phlegm-fire type of insomnia,is to provide clinical basis for further accurate treatment of phlegm-fire type of insomnia and play the long-term advantages of traditional Chinese medicine in treating chronic diseases.Methods:Sixty patients with the phlegm-fire type of insomnia were selected from the department of neurology of first affiliated Hospital of Human University of traditional Chinese Medicine and numbered according to the order of treatment.They were divided into the treatment group and the control group,with 30 cases in each group.The treatment group was treated with self-designed Qingtanningshen decoction,while the control group was treated with Shumian capsule,which was taken continuously for 4 weeks.Observe the Pittsburgh sleep scale(PSQI)and its decrement rate、TCM symptom score、the changes of the safety index and the presence of adverse reactions.Results:1.General information: Before treatment,there was no statistically significant difference in age,gender and course of disease between the two groups of patients,which was comparable.2.PSQI score and effect: Before treatment,2 weeks and 4 weeks after treatment,there was a statistically significant difference in PSQI reduction and the total effective rate between two groups(P<0.05),suggesting that both groups can effectively treat phlegm-fire type of insomnia.The treatment group was better than the control group in improving insomnia symptoms,and the degree of improvement at 4 weeks after treatment was better than 2 weeks after treatment.3.TCM syndrome score and effect: Before treatment,2 weeks after treatment and 4 weeks after treatment,there was a statistically significant difference in the improvement of TCM syndrome scores and the total effective rate between two groups(P<0.05),suggesting that both groups can improve TCM syndrome of insomnia.The treatment group was better than the control group in improving insomnia symptoms,and the degree of improvement at 4 weeks after treatment was better than 2 weeks after treatment.4.Safety evaluation: No obvious adverse reactions occurred in the two groups during the observation period,suggesting that the drug use is safe.Conclusion:In the treatment of phlegm-fire type of insomnia,self-designed Qingtanningshen decoction has better efficacy than Shumian capsule in improving Pittsburgh Sleep Scale(PSQI)and TCM syndrome.and the degree of improvement of symptoms after 4 weeks of treatment is better than that after 2 weeks.The long-term prognosis is more beneficial,safe and reliable,worthy of clinical application.