A Clinical Study On The Effect Of Phlegm - Lowering Calorie Treatment On Generalized Anxiety Associated With Insomnia

Summary:Referencing the TCM Syndrome Observation Table、Hamilton Anxiety Scale、Pittsburgh Sleep Quality Index Rating Scale, to evaluate the patients of the comorbidity of insomnia and anxiety,and observe the clinical treatment efficacy of eliminating phlegm and fire.Evaluate the etiopathogenesis of the comorbidity of insomnia and anxiety and the mechanism of methods of eliminating phlegm and fire on the basis of traditional Chinese medical theory, providing clinical resource and evidence to the standardized treatment of the comorbidity of insomnia and anxiety.Methods:The research follow the rule of evidence-based medicine and take the method of Random parallel control to extract 60 cases as subjects in the study, the patients are in the Encephalopathy out-patient of the 3rd Affiliated Hospital of Beijing University of Medicine from the November,2012 to the December,2014, they were randomly and evenly divided into two groups, control group given lorazepam tablets daily. And treatment group given Chaiqin Wendan Decoction basis on the methods of eliminating phlegm and fire.At the period of treatment, both are not allowed to use any other hypnotics and antianxiety drugs. Before, after treatment for 2 weeks,4 weeks, all use the PSQI score, HAM A score to evaluate sleep quality and to appraise the degree of anxiety and TCM symptoms rating scale evaluation of curative improvement effect. Assess to the side effects of two groups after treatment by using TESS scale score evaluation. Inputs data in Excel and analysis the curative effect of treatment by the using of statistical software SPSS17.0 analysis.Results:In the second and fourth week of study/the PSQI sleep scale score in Chaiqin Wendan Dec oction group is slight superior to the lorazepam group,The HAMA scale score of Chaiqin Wen dan Decoction group is also superior to the control group, the total effective rate of the TCM symptom such as phlegm fire stagnation cured by Chaiqin Wendan Decoction is not less than the control group. During the treatment, several patients in the treatment group once had t he laxativeness or epigastric discomfort, these symptoms could vanish by the adjustment of d oes,and no other obvious side effect.Instead,patients in the control group tended to have so me untoward effect like thirst, sudation, feeling in a daze when wake up in the morning.Conclusion:1. There are same curative effect and less side effect by using methods of eliminating phlegm and fire to treat insomnia and anxiety, prove that Syndrome differentiation treatment of Traditional Chinese Medicine is as good as western medicine.2. Insomnia patients often have anxiety while anxiety disorders have sleep problems.,rather than the causal relationship, they are comorbidity and affecting each other, making the symptoms of anxiety and insomnia more serious.3. The TCM apply the theory of treatment according to syndrome differentiation, discovering the commone pattern of syndrome of the comorbidity anxiety and insomnia is stagnation of phlegm fire type, adopting the method of homotherapy for heteropathy to treat the disease by employing the Chaiqin Wendan Decoction, whose effect include the Eliminating phlegm and fire, removing heat from the liver and gallbladder,harmonizing stomach and relieve uneasiness of mind, regulating yin and yang, clearing away the heart-fire and uncomfortable emotions. Clinical effect can be found in the improvement of insomnia and the control of anxiety.