Retrospective Study On The Treatment Of Chronic Kidney Disease Stage 3-5 With Damp-heat Syndrome Using Zishen Qushi Decoctio

Objective:Retrospective study was used to study the clinical effect of TCM dampness syndrome in the treatment of chronic kidney disease in stage 3-5 of TCM syndrome.Methods:From January 2019 to the outpatient Department of Nephrology Hospital of Liaoning University of Traditional Chinese Medicine and diagnosed with chronic kidney disease stage 3-5 from November 2020 were divided into treatment group and control group,and patients lost to follow-up were removed,with 40 patients in each group.All 80 patients received basic treatments such as low salt,low fat,high quality and low protein diet,preventing infection,correcting ion disorder,correcting anemia,and blood pressure control,On this basis,the treatment group should apply 100 ml wet decoction orally three times a day,Control group applied renal failure Ning granules(Shanxi Deyuantang Pharmaceutical Co.,Ltd.,Approval document no.Z20050503)1 bag three times a day;The improvement of symptoms before and after treatment in both groups,Statistical analysis of the index changes of blood creatinine(Scr),urea nitrogen(BUN),glomerular filtration rate(e GFR),24 h urinary protein quantification before and after treatment in the two groups of cases,Then evaluate the curative effect of zi kidney Juan wet soup.Results:1.TCM syndrome score: the response rate was 72.50% and 47.50% in the control group,and the treatment group was better than the control group(p <0.01);2.Blood creatinine: the effective rate was 80.00%,50.00% in control group,and better than that in control group(p <0.05).3.BUN levels: Both groups were decreased,and the treatment group was better than the control group(p <0.05).4.Glomerular filtration rate: the effective rate of the treatment group was 87.50%,which was52.50%,and the control group was better than the control group(p <0.05).5.24-hour urinary protein quantification: the 24-hour urinary protein quantification was decreased in both groups,and the treatment group was better than the control group(p <0.01);Conclusion:The soup can improve the TCM symptoms of chronic kidney disease in stage3-5,including abdominal distension,thirst,less drinking,less food and less loose stool,effectively reduce blood creatinine,urea nitrogen level,24-hour urine protein quantification,and improve the glomerular filtration rate.