| Objective The method of Clearing heat and benefiting dampness is used to treat non-alcoholic fatty liver disease who is in dampness and heat.The results were recorded for providing evidence for the future TCM treatment of this basicMethods From January 2021 to December 2021,there were One hundred and thirty patients in this study,all of them are from the Third Affiliated Hospital of Zhejiang Chinese Medicine University.They all had obstructive non-alcoholic fatty liver disease in heat and dampness.The patients were divided chronologically into two groups.One group was the observation group.This group was used of clearing heat and invigorating dampness by oraling traditional Chinese medicine.the other group received oral treatment with western medicine.There were 65 people in each group.Both groups received exercise therapy plus a diet control.At the same time,the treatment method of the Chinese medicine observation group was oral Chinese medicine granule to clear heat and reduce humidity,the another group took western medicine,this medicine was called polyene phosphatidylcholine capsules.The treatment lasted eight weeks.After treatment,the ratio of liver/spleen CT and TCM syndrome score were recorded,at the same time,Integral,liver tests in blood（ALT,AST）,blood lipids（TC,TG,HDL-C）and other related indicators,the clinical efficacy was analyzed,and the conclusion was drawn.Results 1.Comprehensive efficacy discovery:the effective rate of TCM group with clearing heat and invigorating dampness was 89.23%.The effective rate of the control group using oral western medicine was 80%.this shows that the effect of the traditional Chinese medicine group using heat-clearing and dampness method is more significant（P<0.01）.2.Comparison of CT values of liver and spleen:After testing,the liver/spleen CT ratio improved in both groups after treatment（P<0.05 in the control group,P<0.01 in the other group）;Compared this two groups,we found that people in the group who using Chinese medicine was mush better in the Liver/spleen CT ratio（P<0.05）.3.Comparison of liver tests in blood（ALT,AST）:ALT and AST in both groups decreased after treatment,this two methods both achieve good influence（P<0.01）.The comparison between the two groups showed that the observation group did better（P<0.01）.4.Comparison of blood lipids（TC,TG,HDL-C）:After treatment,in the observation group,TC,TG and HDL-C improved a lot after clearing heat and invigorating dampness（P<0.01）,Similarly,TG and HDL-C were significantly improved in the group using western medicine（P<0.01）,and TC was improved（P<0.05）.Comparing the two groups,the observation group had significant effect in improving TC and TG（P<0.01）.However,for HDL-C,the results were similar in both groups（P>0.05）5.Total score of TCM symptoms:After treatment,the observation group was improved in yellow urine color of secondary symptoms（P<0.05）,and in total scores,primary symptoms and other aspects of secondary symptoms was much better（P<0.01）.People who in the group of control became much better in the main symptoms of the body weight,abdominal distension or pain,secondary symptoms of urine yellow,sticky mouth（P<0.05）,the total score,other aspects of the main symptoms and other aspects of the secondary symptoms significantly improved（P<0.01）.Compared between the two groups,the two groups had similar treatment effects in terms of sticky stool,yellow body and eyes,and yellow urine（P>0.05）.For all aspects of the primary symptom,the other aspects of the secondary symptom,and total score,the observation group had a greater effect（P<0.01）.6.Safety evaluation:During the treatment,Patients in this two groups are good in blood,urine,fecal routine,electrocardiogram,renal function observation.None of the patients had adverse reactionsConclusion Clearing heat and invigorating dampness is effective in the treatment of this type of non-alcoholic fatty liver disease,It’s also safe. |
PDF Full Text Request