Effect Of Bushen Huatan Prescription Combined With Exercise Therapy On Metabolism In Patients With PCOS-I

Purpose:To observe the improvement of metabolism of patients with polycystic ovary syndrome with insulin resistance by Bushen Huatan formula combined with exercise therapy,and analyze the changes of clinical symptoms and clinical indicators before and after treatment,in order to give theoretical support and therapy options for polycystic ovary syndrome patients with insulin resistance.Method:Between October 2019 and November 2021,a total of 70 patients with pcos-ir,renal deficiency,and phlegm dampness syndrome were randomly recruited from the gynecological clinic of the Affiliated Hospital of Liaoning University of traditional Chinese medicine.With35 patients in each group,the patients were randomly assigned to the observation and control groups.Bushen Huatan Decoction was used to treat the patients in the control group,drospirone ethinylestradiol tablets and metformin hydrochloride tablets.On the basis of the treatment of the control group,the observation group urged the patients to exercise regularly with sufficient intensity according to the guiding scheme.Health education was carried out during the treatment in both groups to urge patients to adopt a healthy lifestyle.For three consecutive cycles of treatment,one menstrual cycle was used as a course of treatment.After treatment,changes in basic indexes,sex hormone levels,glucose metabolism-related indexes,TCM clinical syndrome score,hairiness,and acne symptom score were noted before and after therapy,and the gathered data was statistically evaluated.Results:1.Body weight,BMI,waist circumference,hip circumference,and waist hip ratio: the hip circumference of both groups decreased after treatment,and there was a significant difference between the two groups(P<0.05);there were significant differences in body weight,BMI,and waist circumference between the observation group before and after treatment(P<0.05),and there were significant differences in body weight between the two groups after treatment(P0.05);and there were significant differences in body weight between the two groups after treatment(P<0.05).2.Analysis of glucose metabolism indexes: fasting blood glucose,fasting insulin and HOMA-IR in the two groups decreased after treatment,and HOMA-β.After therapy,the index dropped,and the difference between the two groups was significant(P<0.05).After therapy,there was a significant difference between the two groups in fasting blood glucose,fasting insulin,and HOMA-IR(P<0.05).3.The results of the study revealed that the subjects who received treatment had a significant decrease in the level of LH and LH/FSH,while that who were observed had a significant increase in the FSH between these two groups(P<0.05);T in the observation group decreased after remedy,and there was significant difference in the comparison(P<0.05).There was significant difference in the comparison of LH between the two groups after remedy(P<0.05).4.Comparisons of TCM syndrome score,period symptom score,Ferriman-Gallwey score and Rosenfield score: the TCM syndrome score,period symptom score and Ferriman-Gallwey score in the two groups decreased,and there was a statistical difference between the two groups(P<0.05);There was no clear distinction in relative Ferriman-Gallwey score between the two groups(P>0.05);For Rosenfield score,there was no significant decrease between the two groups(P>0.05).5.Contrasts of traditional Chinese medicine’s comprehensive curative effect: the observation group’s total effective rate was greater than the control group’s before and after remedy(P<0.05).Conclusion:1.Regular exercise with sufficient intensity has significant advantages in the improvement of body weight,fasting blood glucose,fasting insulin,HOMA-IR,LH,TCM symptoms and menstrual symptoms.2.Regular exercise with sufficient intensity has the advantages of simple operation and low cost,which is suitable for universal promotion.