| Objective(s):The protective factors and independent risk factors of malignant arrhythmia in patients of a hospital in Kunming were analyzed to provide a basis for their targeted clinical treatment.Methods:A retrospective approach was used to investigate patients admitted to the emergency department of a Grade A hospital in Kunming from January 1,2013 to May 1,2022.According to the unified requirements,standards and methods to collect AAP patients poisoning data meet the criteria for inclusion and exclusion,divided into malignant arrhythmia group and non-malignant arrhythmia group according to whether the malignant arrhythmia,and compare the general situation of admission,laboratory examination indicators,by SPSS analysis of the patients between the two groups and the protective factors and independent risk factors.Results: A total of 189 patients with acute aconitine poisoning were included,including 53 in the malignant arrhythmia group and 136 in the non-malignant arrhythmia group.There were statistically significant differences in age,past history,MAP,heart rate,finger pulse oxygen saturation,respiratory rate,PSS score,AST,CRE,Lac,Myo,CK-MB,and NT-pro BNP(P <0.05).Among them,increased MAP was the protective factor for malignant arrhythmia in AAP patients(b-0.032,P 0.036,OR 0.969),and increased Lac(b 0.142,P 0.027,OR 1.153),NT-pro BNP(b 0.003,P0.041,OR 1.003)were the independent risk factors.The optimal cut-off for MAP was62(sensitivity 93.4%,specificity 56.6%),Lac was 0.7 mmol/L(sensitivity 100%,specificity 99.3%),and the NT-pro BNP optimal cutoff was 149 ug / L(sensitivity52.8%,specificity 10.3%).Conclusion(s): Increased MAP is a protective factor for malignant arrhythmia in patients with acute aconitine poisoning,and increased Lac and NT-pro BNP are the independent risk factors. |
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