Distribution And Relationship Between TCM Syndrome Type And Constitution Of Children With Henoch-Schonlein Purpura Nephritis In Sichuan

Objective: To obtain the general situation,TCM syndrome type and constitution distribution of children with HSPN in Sichuan by investigating the included cases,and to study on the correlation between TCM syndrome type and constitution,in order to provide theoretical support for the prevention and treatment of disease.Methods: Select the children who visited or were hospitalized in the department of paediatrics of Sichuan TCM Hospital or Jinjiang District of West China Second University Hospital from January 2021 to December 2021 with HSPN as the research objects,based on the conclusion from a questionnaire survey was conducted into the of the TCM syndrome type and constitution,using the WPS software input data,using spss26.0 software analyse data.Result:1.General situation: There were 320 children in the shudy,including 152 girls and168 boys;The average age was 9.27 ± 3.27 years;Disease course within 1 month,114 persons,between 1-6 months,108 persons,more than 6 months,98 persons;There were4 patients with massive proteinuria,10 patients with simple proteinuria,34 patients with simple hematuria and 272 patients with hematuria combined with proteinuria;69patients developed the disease in the spring,67 patients developed the disease in the summe and autumn,117 patients developed the disease in the winter.2.Distribution of TCM syndrome type: 9 cases were Lung-Spleen Qi Deficiency Syndrome,28 cases were Wind-Heat Injuring Collaterals Syndrome,81 cases were Liver-Kidney Yin Deficiency Syndrome,6 cases were Spleen-Kidney Yang Deficiency Syndrome,32 cases were Qi and Yin Deficiency Syndrome,67 cases were Toxin Injurying Kidney Collaterals Syndrome,83 cases were Internal Invasion of DampnessHeat Syndrome,and 14 cases were Dampness and Blood Stasis Interaction Syndrome.The syndrome type was correlated with urine test results and course of disease(P <0.05).3.Distribution of TCM constitution : There were 22 cases of Gentleness type,71 cases of Qi Deficiency type,6 cases of Qi Depression type,69 cases of Damp-Heat type,26 cases of Phlegm-Dampness type,15 cases of Specific Diathesis type,9 cases of Blood Stasis type,22 cases of Yang Deficiency type and 80 cases of Yin Deficiency type.TCM constitution was related to sex,age and urine test results(P < 0.05).4.Relationship between TCM syndrome type and constitution: Yin Deficiency type was correlated with Toxin Injurying Kidney Collaterals Syndrome and LiverKidney Yin Deficiency Syndrome(P < 0.001).Gentleness type was correlated with Wind-Heat Injuring Collaterals Syndrome(P< 0.001),Qi Deficiency type was correlated with Qi and Yin Deficiency Syndrome(P < 0.001),Yang Deficiency type was correlated with Spleen-Kidney Yang Deficiency Syndrome and Internal Invasion of DampnessHeat Syndrome(P < 0.001),Damp-Heat type was correlated with Internal Invasion of Dampness-Heat Syndrome(P< 0.001),Blood Stasis type was correlated with Dampness and Blood Stasis Interaction Syndrome(P < 0.001).Conclusion:1.The syndrome types of children with HSPN are mostly Internal Invasion of Dampness-Heat Syndrome,Liver-Kidney Yin Deficiency Syndrome and Toxin Injurying Kidney Collaterals Syndrome.The syndrome type is correlated with urine test results and course of HSPN.2.The constitutions of children with HSPN are mostly Yin Deficiency type,Qi Deficiency type and Damp-Heat type.The Constitution is correlated with sex,age and urine test results.3.The constitution of children with HSPN is correlated with the syndrome type.Among them,Yin Deficiency type is more common in Toxin Injurying Kidney Collaterals Syndrome and Liver-Kidney Yin Deficiency Syndrome,Qi Deficiency type is more common in Qi and Yin Deficiency Syndrome,Yang deficiency type is more common in Spleen-Kidney Yang Deficiency Syndrome and Internal Invasion of Dampness-Heat Syndrome,Damp-Heat type is more common in Internal Invasion of Dampness-Heat Syndrome.