| Purpose: The present study is aims to observe the clinical efficacy of massage using a single thumb in the treatment of depression after drug addiction,and its impact on the concentration of neurotransmitters(5-HT 、DA 、NE 、E)in patient’s serum.Clarify the mechanism of massage using a single thumb in the treatment of depression,and provide a new treatment method and theoretical basis for clinical treatment of depression.Methods: In this study,80 patients with depression who entered the detoxification rehabilitation period of Rehabilitation Center affiliated to Gansu Province drug treatment administration from October 2020 to April 2021 were randomly divided into a control group of 40 patients and a treatment group of 40 patients.The control group mainly carried out positive education,psychological counseling,health education,supervision and exercise,and nutrition improvement measures for the patients,so that the patients could understand the harm of drugs,and then change psychologically and physically.The treatment group was given Massage using a single thumb on the basis of the control group.After 3 months of treatment,the changes of Hamilton Depression Scale(HAMD)score and 5-HT,DA,NE,E in serum of the two groups were compared before and after treatment,and then conduct statistic alanalysis.Results(1)General information: Before treatment,the gender,age,course of disease,marriage and education of the patients in two groups were statistically compared,and the difference was not statistically significant(P>0.05),which was comparable.(2)Comparison of clinical efficacy: The total effective rate in the control group was77.5%,while the total effective rate in the treatment group was 90%.There was a significant difference in the efficacy(P<0.05),indicating that the massage using a single thumb had a significant effect in treating patients with post drug addiction depression and was superior to conventional treatment.(3)Comparison of HAMD-17 scale scores: The HAMD scale scores were compared between groups before treatment,with no significant difference(P>0.05)and were comparable;After 3 months of treatment,the scores of HAMD scale decreased,and there was a significant difference between the two groups(P<0.05),indicating that the treatment was effective;After treatment,the scores of the HAMD scale were compared between groups,and the score in the treatment group decreased more significantly(P<0.05),indicating that the massage using a single thumb had a significant therapeutic effect in treating patients with post drug addiction depression and was superior to conventional treatment.(4)Comparison of factor scores in various dimensions: Except for the weight of the control group(P>0.05),the other factor scores in the two groups were significantly reduced after treatment,and there was a significant difference between the treatment group and the control group after treatment(P<0.05).The effective rate of each dimension factor in the two groups was significantly different(P<0.05)except for body weight(P>0.05),indicating that the massage using a single thumb was superior to conventional treatment in treating various factor symptoms in patients with post drug addiction depression.(5)Comparison of neurotransmitter concentration: After 3 months of treatment,the concentration of monoamine neurotransmitters(5-HT,DA,NE)in the serum of the two groups were significantly higher than before treatment(P<0.05),while E was slightly lower(P<0.05).Moreover,compared with the control group,the concentration of DA,E,NE in the treatment group after treatment had a significant difference,with a statistically significant difference(P<0.05),indicating that massage using a single thumb could promote the secretion of 5-HT,DA,NE,and reduce the secretion of E.Conclusion: The results showed that massage using a single thumb had a definite effect in the treatment of patients with post-drug addiction depression.It could effect ively reduce the HAMD score of patients with post-drug addiction depression,increa se the concentration of 5-HT,DA,NE in the serum of patients,and reduce the con centration of E,so that the patients’ depressive symptoms could gradually recovery i n physiologically and psychologically,and there was no adverse reaction in clinical observation. |
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