Objective:This topic focuses on the knee osteoarthritis which is identified as cold-dampness obstruction syndrome,to explore the effectiveness,persistence and safety of Wentong Zhitong sticking-plaster by its therapeutic effect and to find a better clinical treatment method for the patient of cold-dampness obstruction syndrome of knee osteoarthritis.Methods:To select 60 representative KOA patients who met the case screening criteria from September 2021 to September 2022 in the department of joint orthopedics of Jiangxi Province Hospital of TCM.The patients were split at random into the treatment and the control group,each 3O cases.Under the treatment of the two grops.On one hand,the treatment group used Wentong Zhitong sticking-plaster to treat.On the other hand,the control group was treated with Flubiprofen Gel Paste(NSAIDs).Both groups were applied around the knee joint according to the patient’s pain part,and the knee pad could be fixed externally to avoid falling off.The treatment frequency of both groups was once a day and applied in the morning for2 weeks.Before and after treatment and follow-up,to observe and record the VAS,WOMAC,TCM syndrome scores and clinical efficacy,the organized data are statistically analyzed with SPSS25.0,which will be applied to evaluate the short-term clinical efficacy of the different methods.Results:1.After analyzing the two groups’ baseline data,VAS,WOMAC and TCM syndrome scores before treatment by SPSS25.0 statistical software,there was no statistical difference(P>0.05),which showed the two groups were comparable and feasible for further research.2.Comparison within the two groups: After 2 weeks,the two groups’ VAS,WOMAC and TCM syndrome scores were all lower than those before.In addition,SPSS25.0 statistical software’s analysis showed that the differences were statistically significant(P<0.01),further proving that the treatment group and the control group achieved ideal results after treatment.3.Comparison between the two groups:SPPS25.0 statistical software was used to severally compare the VAS,WOMAC and TCM syndrome scores of the two groups after 2 weeks: in addition to VAS score,the rest of the scores of the patients in the Wentong Wentong Zhitong sticking-plaster group were lower than the other group,and the differences showed significant statistical significance(P<0.01),proving that the two groups had the same effect in relieving keen pain and the Wentong Wentong Zhitong sticking-plaster group had better effect in relieving the function and the symptoms of TCM than that of the control group.4.Comparison of clinical effects between the two groups:According to the SPSS25.0 analysis,the two groups’ total efficiency difference had statistically significant(P<0.05).5.During the follow-up,We recorded the two groups’ scores of the VAS,WOMAC score and TCM syndrome again,and which were compared with the three terms scores just after treatment by SPPS25.0 statistical software respectively.It can be obtained that the difference between the above three scores in the treatment group had no statistical significance(P>0.05),and the difference between the follow-up and post-treatment is very small,which indicated that the recurrence rate of patients in the treatment group is low.On the contrary,after the analysis of SPSS25.0Results:statistical software,it can be obtained that the control group’s three scoring results of the follow-up than before had significant statistical differences(P<0.01),which showed that the Flubiprofen Gel Paste group’s efficacy is unsustainable and has a higher probability of recurrence than the Wentong Zhitong sticking-plaster group.Conclusion:1.Wentong Zhitong sticking-plaster and Flubiprofen Gel Paste all have achieved obvious results in the short-term clinical treatment of cold-dampness obstruction syndrome of KOA.2.The overall efficiency of the therapy of cold-dampness obstruction syndrome of KOA in the Wentong Zhitong sticking-plaster group is higher than the other group.The therapy of Wentong Zhitong sticking-plaster external application has obvious advantages in improving knee swelling and pain,dysfunction,knee stiffness and TCM syndrome-related symptoms in the short term,and the recurrence rate is low.There are no obvious adverse reactions,which is of safety.This provides a new idea for clinical treatment of cold-dampness obstruction syndrome of KOA in traditional Chinese medicine,which is worth popularizing. |