| Objective: From the angle of Jin,this study based on the theory of Wentong Shujin.To observe the clinical efficacy and safety of oral Chinese medicine combined with “four-step stretching method”functional exercise in the treatment of knee osteoarthritis of wind-cold-dampness arthralgia type.Methods: This subject adopts a randomized,controlled study method.From November 2018 to November 2019,80 patients diagnosed with knee osteoarthritis who met the standard were treated in the outpatient clinic of Henan traditional Chinese Medicine Hospital.They were randomly divided into treatment group(40 cases)and control group(40 cases).Treatment group : "Wen Tong Shu Jin " as the treatment method,given oral Chinese medicine(Huangqi Guizhi Wuwu decoction and Sini decoction)combined with " four-step extension of tendons method " functional exercise;Control group: oral losuprofen sodium tablets combined with glucosamine sulfate capsules combined with quadriceps equal length contraction training.Both groups were treated for 6 weeks.Observed indicators:WOMAC knee score(including pain score,joint stiffness score,daily activity function score,total score),knee passive activity before and after treatment,total effective rate and safety indicators(blood routine,liver and kidney function,Incidence of adverse events).The collected data were statistically analyzed for efficacy and safety evaluation.Results: A total of 80 samples were included in this study,and 77 cases were finally observed.1.Before treatment,the sex,age,course of disease,knee distribution and X line grading data of the two groups were not statistically significant.2.Before treatment,there was no statistically significant difference in pain score,stiffness score,daily function score and WOMAC total score between the two groups(p>0.05).After treatment,the scores of each dimension and WOMAC in the two groups were significantly reduced compared with those before treatment,with significant difference(p<0.01).The stiffness score,daily function score and WOMAC total score of the treatment group were significantly lower than those of the control group(p<0.01).The pain score of the treatment group was lower than that of the control group,but the difference was not statistically significant(p>0.05).3.Before treatment,the knee passive activity was compared between the two groups(p>0.05).After treatment,intra-group comparison showed that the range of motion of the joints of the two groups increased significantly compared with the previous,with significant difference(p<0.01).After treatment,the activity level of the treatment group was greater than that of the control group,and the difference was statistically significant(p<0.05).4.The total effective rate after treatment was 92.31% in the treatment group,which was higher than 84.21% in the control group,and the difference was statistically significant(p<0.05).5.Before and after treatment,the results of safety index examination in both groups were within the normal range.Incidence of adverse reactions during the study period was 2.56% in the treatment group and 21.05% in the control group,the difference was statistically significant(p<0.05).Conclusion:Both of the two treatments are effective for type knee osteoarthritis of wind-cold-dampness arthralgia.The total effective rate of the treatment group was 92.31%,which was better than that of the control group,and the safety was higher.In terms of pain relief,the combined Chinese medicine program under the guidance of Wentong Shujin method is quite effective with oral losuprofen sodium tablet combined with glucosamine sulfate capsule.In improving the range of motion and the function of daily activities,the method of wentong shujin has more advantages. |
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