The Study Of Quantitative Electroencephalogram In Predicting Ineffective Vascularization After Endovascular Treatment In Acute Cerebral Tnfarction

Objective To explore the correlation between prognosis and early parameters of quantitative electroencephalogram(EEG)in patients treated with ACI arterial blood vessel.To determine whether changes in parameters related to quantitative EEG after ACI arterial blood vessel therapy can be used as an early signal of poor prognosis of patients,and to guide clinicians to accurately judge the disease situation.Method From October 2021 to December 2022,28 patients with acute ischemic stroke admitted to the neurology department of our hospital within 24 hours of onset were collected,including 23 males and 5 females,with an average age of 64.86±13.87 years.Patients were monitored and treated in the neurological intensive care unit after endovascular treatment.The management and treatment of patients were carried out according to the "Chinese Guidelines for the Prevention and treatment of Stroke(2021 edition)".All patients completed 24-hour electroencephalogram monitoring immediately after surgery.The whole-brain delta/alpha ratio(DAR),(delta + theta)/(alpha + beta)ratio(DTABR)and relative band power were analyzed,and clinical and laboratory data were collected.According to the m RS Score at 90 days,the patients were divided into the effective recanalization group(m RS<3 points)and the ineffective recanalization group(m RS ≥ 3 points).The differences in baseline data and quantitative EEG data between the two groups were compared,and the correlation analysis was performed by binary logistics regression equation.ROC curve was used to evaluate the predictive value of the indicators in the regression model,and Pearson or Spearman was used to analyze the correlation between EEG indicators according to their data distribution.Result1.A total of 28 patients with ACI and 21 patients(75%)with thrombolysis were included in this study,including 18 patients(64.2%)in the effective operation group and 10patients(35.7%)in the ineffective operation group.There were no significant differences in baseline data of gender,age,infarct side,systolic blood pressure,diabetes history,smoking history,history of atrial fibrillation,history of stroke,time from onset to thrombolysis,low density lipoprotein and homocysteine between the two groups(P>0.05)2.The preoperative NIHSS score was 17.90±4.65 in the ineffective recanalization group and 15.00±3.96 in the effective recanalization group(P>0.05).The NIHSS score at 24 hours after thrombectomy in the ineffective recanalization group was 20.90±4.73,which was higher than 8.89±3.18 in the effective recanalization group(P<0.05).The NIHSS score 7 days after thrombectomy was 19.40±5.46 in the ineffective recanalization group,which was higher than7.94±2.34 in the effective recanalization group(P<0.05).3.The relative power of α band and β band of quantitative EEG was negatively correlated with postoperative NIHSS score(P<0.05).The relative power of δ band,DAR and DTABR were positively correlated with postoperative NIHSS score(P<0.05).4.The relative power of α-band in the ineffective switched group was 0.12±0.05,which was lower than that in the effective switched group(0.22±0.07,P<0.05).The relative power of β-band in ineffective opening group was 0.12±0.06,which was lower than that in effective opening group(0.21±0.06),P<0.05.The relative power of δ band in ineffectually switched group was 0.54±0.05,which was higher than that in effectively switched group(0.38±0.07,P<0.05).DAR(OR=2.831,95%CI: 1.82-5.801,P<0.05),DTABR(OR=7.721,95%CI:1.926-30.947,P<0.05),and the optimal cut-off values of DAR and DTABR were 3.48 and1.86,respectively.Conclusion1.The early parameter changes of quantitative EEG can predict the prognosis of ACI patients after EVT.2.Quantitative EEG related parameters are closely related to NIHSS score after EVT in ACI patients.3.DAR and DTABR were independent risk factors for the prognosis of patients with ACI after EVT,and they were positively correlated with the occurrence of ineffective patency.4.The value of DTABR for ineffective opening is higher than that of DAR,and patients with DTABR≥1.86 are more likely to have poor prognosis.