Clinical Study On The Effect Of Huayu Tongluo Method In The Treatment Of Diarrhea(Spleen And Kidney Yang Deficiency)

Research objective: The objective of this study was to compare the effectiveness and safety of several different treatments,removing blood stasis and dredging collaterals formula and Sishen ball,for patients with spleen-kidney yang deficiency type diarrhea.The aim was to provide a safe and effective clinical treatment method with a high cure rate and low recurrence rate,to alleviate the suffering of diarrhea(spleen-kidney yang deficiency type)patients,and ultimately achieve a curative effect.Research methods: Patients who met the inclusion criteria were randomly assigned to the treatment group,which received the Removing blood stasis and dredging collaterals formula orally,or the control group,which received Sishen Ball orally.The specific formula for Removing blood stasis and dredging collaterals formula included Buguzhi,Wuzhuyu,Weiroukou,Wuweizi,Wumei,Tufuling,Baizhu,Houpo,Chuanxiong,Danggui,Guizhi,and Dazao.The control group received Sishen Ball(27g/bottle * 10 bottles/box,produced by Beijing Tongrentang Natural Medicine(Tangshan)Co.,Ltd.,approval number:National Drug Approval Z13020656)orally.Both the treatment and control groups were treated for 2 courses,for a total of 28 days.The medication was taken once daily,30 minutes before breakfast and 30 minutes after dinner.After 2 courses of treatment,the clinical symptom scores before and after treatment were compared between the two groups to observe the treatment effect,and the patients were followed up after 4 weeks to record their symptom scores.In the end,statistical analysis was used to compare the scores for statistical significance.Research results: A total of 64 patients with spleen-kidney yang deficiency-type diarrhea were included in the research,with 32 in each group.Before treatment,there were no statistically significant differences in patient gender,age,and various clinical symptoms like abdominal pain and diarrhea(number of times per day),which could be compared.After 2 courses of treatment,there were 10 cured patients,12 markedly effective patients,6effective patients,and 4 ineffective patients in the treatment group,with a total effective rate of 87.5%.In the control group,there were 6 cured patients,11 markedly effective patients,8 effective patients,and 7 ineffective patients,with a total effective rate of 78.13%.Both groups of patients presented a decreasing trend in symptom scores after treatment,but the decrease in total symptom scores in the treatment group was greater than that in the control group,with a P value of <0.05,which was statistically significant.The treatment group showed a more significant improvement in the four main symptoms of abdominal pain,diarrhea(number of times per day),stool characteristics,and fatigue than the control group after treatment,and this improvement persisted during the 4-week follow-up period after symptom resolution.Moreover,no discomfort or adverse reactions were reported during the treatment observation period in either group.Research conclusion: removing blood stasis and dredging collaterals formula is a more effective treatment for spleen-kidney yang deficiency type diarrhea,and the " removing blood stasis and dredging collaterals formula method" is a treatment method that is worth promoting in clinical practice.