Clinical Significance Of Coagulation Function Index In DVT And Its Correlation With TCM Syndrome Types

Objective:To explore the clinical significance of coagulation function index in deep vein thrombosis of lower limbs and its correlation with TCM syndrome types.Methods:One hundred and thirty-two eligible DVT patients from the Department of General Surgery I of the First People’s Hospital of Yunnan Province（Kunhua Hospital）were randomly selected as the observation group,while one hundred and thirty-two other non-DVT health checkups were selected as the control group,and the basic data（gender,age,site of onse,stage,body mass index,blood type,smoking/drinking history,past medical history,predisposing factors）and laboratory measurement data（PT,INR,FIB,APTT,TT,DD₂）.Study content:（1）To compare the differences between the observation group and the control group regarding the above study indicators and to study their clinical significance in the formation of DVT using statistical methods;（2）To divide the observation group into three groups,namely,61 cases with damp-heat downstream evidence,34 cases with blood vessel stasis evidence and 37 cases with qi deficiency and dampness blocking evidence,and to observe the expression and diagnostic value of the study parameters on the different types of TCM symptoms.Results:（1）After the two groups were counted,there were no statistically significant differences in age,gender,blood type,smoking/drinking history,and past history（hypertension,diabetes）（p>0.05）;there were significant differences in PT,INR,FIB,and DD₂comparisons（p<0.01）,TT comparisons（p<0.05）,and no differences in APTT comparisons（p>0.05）.（2）In patients with DVT,the FIB levels of the damp-heat downstream evidence,blood vessel stasis evidence and qi deficiency and dampness blocking evidence decreased in order,which was statistically significant（p<0.05,p<0.01）,and the DD₂level of damp-heat downstream evidence was also much higher than the blood stasis syndrome（p<0.01）,but other coagulation indexes were not statistically significant（p>0.05）.Conclusion:PT,INR,FIB,DD₂,and TT are related to deep vein thrombosis,especially FIB and DD₂are closely related to TCM syndrome types,which provides a clinical reference value for the identification and typing of TCM syndrome types.