Correlation Between The Degree Of Coronary Stenosis And PLR,PDW And MPV In Patients With Blood Stasis Syndrome Of Stable Angina Pectoris In Coronary Artery Disease

Objective:By exploring the differences between serum PDW,MPV and PLR levels in patients with stable angina pectoris and non-blood stasis,and the correlation between the degree of coronary stenosis and PDW,MPV and PLR,this paper provides new ideas for clinical research on the pathogenesis of blood stasis in coronary heart disease and provides a reference for early assessment of the risk of coronary stenosis in patients.Methods:Patients who underwent coronary CTA(coronary CTA)in the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine were selected due to suspected coronary heart disease due to onset of chest pain between March 2022 and March 2023.According to the inclusion and exclusion criteria,166 participants were enrolled,and patients with coronary heart disease were divided into blood stasis group and non-blood stasis group according to the "Diagnostic Criteria for Blood Stasis of Coronary Heart Disease".Collect basic patient information,relevant auxiliary examination data,and coronary CTA data.Data processing and statistical analysis tools were Excel,SPSS 26.0 and Med Calc statistical software Results:1.There were no significant differences in gender,age,alcohol history,diabetes history,and hypertension between the blood stasis group and the non-blood stasis group(P>0.05).The smoking history of the two groups was significantly different(P<0.05)2.Compared with the non-blood stasis syndrome group,the levels of PDW and MPV were significantly higher in patients with stable angina pectoris in coronary artery disease,and the difference was statistically significant(P < 0.01).there was no significant change in PLR levels,and the difference was not statistically significant(P > 0.05).3.The results of correlation analysis showed that blood stasis syndrome was correlated with coronary stenosis degree grading in patients with stable angina in coronary artery disease compared with the non-blood stasis syndrome group(P<0.05).The levels of PDW and MPV were positively correlated with the degree of coronary stenosis grading in patients with blood stasis syndrome(R2> 0,P< 0.05),and the level of PLR was not statistically significant(P> 0.05).4.The area under the ROC curve for PDW was 0.712,with a maximum diagnostic index of 13.05 at a sensitivity of 72% and specificity of 65.8%.the area under the ROC curve for MPV was 0.708,with a maximum diagnostic index of 11.05 at a sensitivity of 61.3% and specificity of 75.3%.the area under the PLR index curve was 0.427,with a sensitivity of 7.5% and specificity of 202.78.The maximum diagnostic index was 202.78 at a sensitivity of 7.5% and specificity of 98.6%.Conclusion:1.Patients with blood stasis syndrome of stable angina pectoris in coronary artery disease had higher PDW and MPV levels compared with those without blood stasis syndrome.2.Patients with blood stasis syndrome of stable angina pectoris in coronary artery disease may be more likely to develop coronary stenosis than those with non-blood stasis syndrome3.Coronary stenosis classification was positively correlated with PDW and MPV in the CHD blood stasis syndrome group,indicating that PDW and MPV levels could predict the degree of coronary stenosis in patients with CHD blood stasis syndrome group.