| Objective:The distribution of TCM syndrome types in patients with unstable angina pectoris in our hospital was analyzed,and the differences of general data and physicochemical indexesin patients with different TCM syndrome types were discussed,so as to provide reference for clinical differentiation of unstable angina pectoris.Methods:A total of 513 patients admitted to the Second Department of Cardiovascular Science and Technology in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from September 2019 to September 2022 were collected,who met the standard of treatment and were diagnosed as coronary heart disease unstable angina pectoris by Western medicine and chest arthralgia and heartache by Chinese medicine.Clinical data of patients were collected and analyzed,including general data such as patient gender,age,solar terms of incidence,predisposing factors,course of disease,smoking history,drinking history,conditions associated with other diseases,and physical and chemical indicators.Statistical software SPSS26.0was used to analyze and compare the differences and correlation between the above data among TCM syndrome types.Results:1.Among the included patients patients was 161(31.38%)with cardiac qi deficiency,153(29.82%)with qi and Yin deficiency,87(16.96%)with phlegm and blood stasis syndrome,64(12.48%)with qi deficiency and blood stasis,and 48 with blood stasis(9.36%).2.The distribution of the ratio of male to female in each syndrome type was as follows: the syndrome of phlegm-stasis interlocking was 1.289,the syndrome of blood stasis interjunction was 1.000,the syndrome of qi deficiency and blood stasis was 0.684,the syndrome of deficiency of heart and qi was 0.578,and the syndrome of qi and Yin deficiency was 0.297,with significant differences(P < 0.05).3.Among the included patients,the maximum age was 95 years,the youngest age was 38 years,and the mean age was 66.95 years.The age distribution of each syndrome type varied significantly(P<0.05),and the number of patients aged 60 to 70 years was the largest.4.In terms of seasons,statistics showed that the disease occurred in all seasons,but most of them were in summer and autumn.5.In terms of the causes of the disease,a total of 513 patients were counted in seven types of inducements: 258 people(50.29%)without cause,201 people were tired(39.18%),33 people were emotionally irritable(6.43%),9 people had a cold(1.76%),7 people were frightened(1.36%),and 3 People(0.58%)and 2 people with diarrhea(0.39%).6.The shortest course of the disease is 3 days,the longest is 39 years,and the average course of the disease is 6.41 years.The number of patients with a course of less than 5 years is the largest,and there is no statistical difference between each syndrome type and the course of the disease.7.The total number of people with a history of smoking is 80,accounting for 15.59% of the total number of people,and there is no statistical significance between the syndrome distribution(P>0.05);the total number of people with a history of drinking is 64,accounting for 12.48% of the total number,and there is statistical significance between the syndrome distribution(P<0.05).8.Among the 513 patients included this time,the top five patients with the disease from high to low were: 336 people with hypertension(65.49%),314 people with interstitial cerebral infarction(61.21%),139 people with diabetes(27.10%),106 people with arrhythmia(20.66%),and 98 people with chronic gastritis(19.10%).9.Among the physical and chemical indicators,triglycerides,total cholesterol,uric acid,homocysteine,average hemoglobin amount,average hemoglobin concentration,red blood cell distribution width,and distribution of glycated hemoglobin among various syndrome types of traditional Chinese medicine are of statistical significance(P<0.05).In the comparison between triglycerides,there are obvious differences between phlegm and blood stasis syndrome and the other four groups(P<0.05);In the comparison between the total cholesterol groups,there are obvious differences between phlegm and qi deficiency syndrome and qi deficiency syndrome(P<0.05);in the comparison between uric acid groups,the difference between phlegm and stasis syndrome and qi and yin deficiency syndrome is obvious(P<0.05);In the comparison between homocysteine groups,there was an obvious difference between the mutual syndrome of phlegm and yin deficiency syndrome and qi and yin(P<0.05);in the comparison of the average amount of hemoglobin,there was a significant difference between the two deficiency syndrome and phlegm and stasis(P<0.05);In the comparison of the average hemoglobin concentration groups,there are obvious differences between phlegm and yin deficiency syndrome and heart qi deficiency syndrome(P<0.05);In the comparison between the red blood cell distribution width groups,there was a significant difference between qi deficiency and blood stasis syndrome and other four groups(P<0.05);in the comparison between glycated hemoglobin groups,there was a significant difference between qi deficiency and blood stasis syndrome and other four groups(P<0.05).10.After multi-factor logistic regression analysis,in the comparison of cholesterol levels,the total cholesterol level of heart qi deficiency syndrome is significantly lower than that of phlegm and blood stasis,indicating that total cholesterol is a risk factor affecting phlegm and stasis;In the comparison of uric acid levels,the uric acid level of Qi and Yin deficiency syndrome is significantly lower than that of phlegm and blood stasis,indicating that uric acid is a risk factor affecting the combination of phlegm and blood stasis;In the comparison of homocysteine levels,the homocysteine level of phlegm and blood stasis is significantly higher than that of qi and yin deficiency syndrome,suggesting that homocysteine is a risk factor affecting phlegm and stasis;In the comparison of the distribution width of red blood cells,the distribution width of qi deficiency and blood stasis syndrome is significantly higher than that of heart qi deficiency syndrome and yin deficiency syndrome,suggesting that the distribution width of red blood cells is a risk factor affecting qi deficiency and blood stasis syndrome;In the comparison of glycated hemoglobin levels,the glycated hemoglobin level in qi deficiency and blood stasis syndrome is significantly higher than that of phlegm stasis and heart qi deficiency syndrome,suggesting that glycated hemoglobin is a risk factor affecting qi deficiency and blood stasis syndrome.Conclusion:1.The distribution of the number of TCM syndromes of 513 patients with unstable angina pectoris is from high to low: heart qi deficiency syndrome,qi and yin deficiency syndrome,phlegm and blood stasis syndrome,qi deficiency and blood stasis syndrome,and heart and blood stasis syndrome.There are significant differences in the distribution of gender,age and drinking history in general data.2.There are significant differences in the distribution of gender,age and drinking history in general data.3.In this study,there were differences between triglycerides,total cholesterol,uric acid,homocysteine,average hemoglobin amount,average hemoglobin concentration,red blood cell distribution width,and glycated hemoglobin between various syndrome types of traditional chinese medicine.Among them,total cholesterol,uric acid and homocysteine are the risk factors affecting the mutual syndrome of phlegm and blood stasis,and the distribution width of red blood cells and glycated hemoglobin are the risk factors affecting the syndrome of qi deficiency and blood stasis. |
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