Analysis Of TCM Syndrome Distribution Characteristics Of Unstable Angina Pectoris Of Coronary Heart Disease

Objective:To observe the distribution of TCM syndromes i n patients with unstable angina pectoris of coronary heart disea se,to study the difference of physical and chemical indexes in the distribution of syndromes,and to find the risk factors relat ed to the distribution of syndromes.Methods:The electronic medical records of 416 patients ad mitted to the First Affiliated Hospital of Heilongjiang Universit y of Chinese Medicine from July 2020 to July 2021 who were d iagnosed as coronary heart disease unstable angina pectoris by Western medicine and chest pain by Chinese medicine were coll ected.Clinical data were collected by the investigator using a u niform questionnaire.SPSS 26.0 statistical software was used to compare the differences between groups in CHD risk factors an d related laboratory test results(C-reactive protein,hypersensiti ve C-reactive protein,mean platelet volume,blood lipid,coagul ation function,etc.)of each syndrome type,and analyze the cor relation between the above laboratory test and TCM syndrome t ype.Results:1.416 patients with unstable angina pectoris of coronary he art disease showed the distribution of TCM syndromes as follow s:qi deficiency and blood stasis syndrome>qi deficiency and blood stasis syndrome>phlegm turbidness and blood stasis syn drome>Qi deficiency and blood stasis syndrome>Qi stagnati on and blood stasis syndrome and phlegm syndrome.2.In general data,there was significant difference in gender distribution of syndrome types(P<0.05).In male patients,the syndrome of qi deficiency and blood stasis was the main one,f ollowed by phlegm turbidness and blood stasis and qi and Yin deficiency combined with blood stasis.3.From high to low,the top 5 diseases were hypertension(56.2%),cerebral infarction(49.9%),diabetes(19.7%),arrhythmi a(18.8%)and heart failure(7.9%);4.The age distribution of patients of all TCM syndromes wa s 61 to 70 years old,and the prevalence rate showed an up war d trend from 50 years old.The average age was 67.28,the olde st was 95,and the youngest was 33.5.The patients with the shortest course of disease were new patients,the longest was 39 years,with an average of 6.61 ye ars.The patients with the shortest course of disease were the m ost patients with the shortest course of disease less than 5 year s.6.In electrocardiogram examination,patients with ST segme nt descent,arrhythmia and abnormal Q wave electrocardiogram c hanges had a higher proportion of patients with qi stagnation a nd blood stasis syndrome.The proportion of patients with qi st agnation,blood stasis and phlegm syndrome was higher in patie nts with RBBB,ST segment low level and T wave inverted ECG changes.7.There was no statistically significant difference between c ardiac ultrasonography,abdominal ultrasonography and cervical u ltrasonography and TCM syndrome type distribution(P>0.05);8.Follow-up:170 patients were not re-ho spitalized from dis charge to February 15,2022,16 patients were re-hospitalized w ithin 1 month,24 patients were re-ho spitalized within 1-3 mont hs,54 patients were re-hospitalized within 3-6 months,52 patie nts were re-hospitalized within 6-1 months,4 patients died,and 95 patients were not connected.9.In physical and chemical indexes,there were no statistica 1 differences between high density lipoprotein,triglyceride,lipo protein(A),low density lipoprotein,uric acid,C-reactive protei n,hypersensitive C-reactive protein,mean platelet volume,fibri nogen,partial thrombin time and TCM syndrome types(P>0.05);There were differences in cholesterol,apolipoprotein B and gly cosylated hemoglobin in qi deficiency,blood stasis and phlegm syndrome(P<0.05).There were differences in homocysteine betw een phlegm turbidness and blood stasis syndrome and qi stagnat ion,blood stasis and phlegm syndrome(P<0.05).There was diff erence in d-dimer between qi stagnation and blood stasis syndro me and Qi and Yin deficiency combined with stasis syndrome(P<0.05).10.Glycosylated hemoglobin is a risk factor affecting the di stribution of qi deficiency and blood stasis syndrome,Qi stagna tion and blood stasis combined with phlegm syndrome,and Qi d eficiency and blood stasis combined with phlegm syndrome;Ho mocysteine was a risk factor for the distribution of qi and Yin deficiency syndrome,qi stagnation and blood stasis combined wi th phlegm,Qi and Yin deficiency combined with blood stasis sy ndrome,phlegm turbidness and blood stasis,qi deficiency and b lood stasis syndrome.Cholesterol is a risk factor for distributio n of qi and Yin deficiency syndrome,qi deficiency and blood s tasis syndrome.Conclusion:1.The results of this study showed that the distribution of TCM syndromes in patients with CHD unstable angina pectoris was qi deficiency and blood stasis syndrome>Qi and Yin defi ciency syndrome>phlegm turbidities and blood stasis syndrome>Qi deficiency and blood stasis syndrome and phlegm syndro me>Qi stagnation and blood stasis syndrome and phlegm syndr ome.2.In general data,there are significant differences between genders in the distribution of TCM syndromes.3.In this study,there were significant differences in the dis tribution of total cholesterol,apolipoprotein B,hBA1c,homocys teine and D-dimer among TCM syndromes;Total cholesterol,gly cosylated hemoglobin and homocysteine were the risk factors aff ecting the distribution of TCM syndrome types.