Clinical Observation Of Self-made Bushen Tongluo Decoction In The Treatment Of Chronic Glomerulonephritis (Liver And Kidney Yin Deficiency And Blood Stasis Type)

Objective:In this project,the clinical efficacy of self-propensed renal tonic prescription in the treatment of chronic glomerulonephritis(liver and kidney yin deficiency and blood stasis)was observed,this topic discusses its role in reducing TCM syndrome scores,improving proteinuria,improving hematuria,and protecting renal function,and provides new ideas for clinical treatment of chronic glomerulonephritis.Methods:In this study,60 patients with chronic glomerulonephritis of liver and kidney yin deficiency and blood stasis type were selected from December2021 to December 2022 in the Department of Nephrology,Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Hebei Province.According to the randomized parallel controlled clinical study design method,the patients were assigned to therapy group(n=30)and study group(n=30).The therapy group was treated with Bushen Tongluo Decoction on the basis of conventional treatment,and the study group was treated with conventional basic treatment.After 8 weeks of treatment,the changes of TCM syndrome scores,renal function related indexes(Scr,BUN,UA),24-hour urinary protein quantification(24h UPro),urinary sediment red blood cell count(RBC),serum albumin(ALB)and other changes were observed before and after treatment.SPSS26.0 statistical software was used for analysis,P<0.05 was considered statistically significant.Results:1.There were no statistical differences in the common data,TCM syndrome scores and laboratory indices between the two arms before treatment(P > 0.05),which were comparable.2.The effective rate of TCM syndromes in the treat group was 83.33%,and that in the contrast group was 60.00%.The effective rate of clinical efficacy in the treated groups was 90.00%,and that in the compare group was 70.00%.There was a statistics difference between the two groups(P <0.05).3.Posttreatment,the total integrated of TCM syndromes in the two arms were lower than before,and there was a significant difference between the two groups(P < 0.01).Compared between groups,the treatment group decreased more(P < 0.05).4.Posttreatment,the points of single TCM syndromes in the two arms were improved to varying degrees,and the difference between the two arms had statistic significance(P < 0.05).Posttreatment,the treat group was superior to the contrast group in improving symptoms such as lumbar spinal pain,five upset heat,dry mouth and throat,dizziness,tinnitus,lumbar tingling,and dark complexion.The difference was statistically significant(P< 0.05).There was no significance between the two arms in improving symptoms such as dry eyes and skin nails(P > 0.05).5.After treatment,the two groups of patients had improved the indexes of Scr,BUN,UA,24 h UPro,RBC,ALB and other indexes(P < 0.05),and the therapyt group was better(P < 0.05).6.There were few adverse reactions and high safety in the two groups before and after treatment.There was no significant difference in safety indicators before and after treatment(P > 0.05).Conclusions:1.Self-made Bushen Tongluo Decoction in the treatment of chronic glomerulonephritis(liver and kidney yin deficiency and blood stasis type),can significantly reduce the TCM syndrome score.2.Self-made Bushen Tongluo Recipe can more effectively reduce24-hour urinary protein quantification,urinary sediment red blood cell count,improve renal function,and increase serum albumin in patients with chronic glomerulonephritis(liver and kidney yin deficiency and blood stasis type).3.The curative effect of self-made Bushen Tongluo Decoction in the treatment of chronic glomerulonephritis(liver and kidney yin deficiency and blood stasis type)is significant,with less adverse reactions,which is worthy of clinical promotion.