| 1.PurposeTo observe the clinical efficacy of Wuqinxi combined with lifestyle in the prevention and treatment of Grade 1 essential hypertension,confirm the feasibility of Wuqinxi combined with lifestyle intervention in Grade 1 essential hypertension,and provide objective basis for the treatment.2.MethodsSixty-six patients with grade 1 essential hypertension who met the inclusion criteria were collected and randomly divided into observation group and control group according to random number table method,31 cases were actually completed in observation group and 30 cases in control group.The control group was treated with lifestyle intervention,and the observation group was treated with lifestyle intervention combined with Wuqinxi(5 days/week,6 sets a day,3 sets in the morning and 3 sets in the evening).The treatment cycle of both groups was 12 weeks.The changes of blood pressure,ambulatory blood pressure,PRA,ALD,AngⅡ,and Duchenne hypertension Quality of Life scale before and after intervention were compared.3.Results(1)Comparison before intervention: there was no statistical significance in the comparison of baseline data between the two groups(P>0.05),indicating comparability.There was no statistical significance in clinic blood pressure,ambulate blood pressure,Duchenne hypertension quality of life score and hypertension(PRA,ALD,Ang Ⅱ)between the two groups(P>0.05),indicating comparability.(2)Comparison after intervention: Comparing the blood pressure,PRA,AngⅡ,ALD levels and Duchenne hypertension quality of life score of the two groups,the differences between the two groups were statistically significant(P<0.05),indicating that the two groups of intervention can reduce the levels of blood pressure and hypertension(PRA,AngⅡ,ALD),improve the quality of life of patients.Moreover,the treatment effect of Wuqin Opera combined with lifestyle is better than that of simple lifestyle intervention.(3)Comparison of ambulate blood pressure after intervention: there were statistical differences in the whole-day average blood pressure,daytime average blood pressure and nighttime average systolic blood pressure between the two groups(P<0.05).The average diastolic blood pressure at night in the observation group was statistically different(P<0.05),while the average diastolic blood pressure at night in the control group was not statistically significant(P>0.05),indicating that all intervention methods could reduce the average blood pressure throughout the day,the average daytime blood pressure and the average systolic blood pressure at night.In addition,the control group had no significant effect on nocturnal average diastolic blood pressure.The difference between the two groups was statistically significant(P<0.05),indicating that the treatment effect of the observation group was better than that of the control group.(4)Comparison of the total effective rate of antihypertensive efficacy between the two groups: After intervention,the total effective rate of the observation group was 80.65%,and the total effective rate of the control group was 36.67%,the difference was statistically significant(P<0.05),indicating that the observation group was superior to the control group in terms of efficacy.4.Conclusion(1)Wuqinxi combined with lifestyle intervention and lifestyle intervention has therapeutic effect on grade 1 essential hypertension.(2)Wuqinxi combined with lifestyle intervention is superior to lifestyle intervention in improving quality of life,hypertension and blood pressure control of patients with grade1 essential hypertension. |
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