Clinical Characteristics Analysis Of 40 Cases Of Chlamydia Psittaci Pneumonia

Objective:The clinical characteristics of 40 cases of Chlamydia psittaci pneumonia were analyzed to improve the diagnosis and treatment of the disease.Methods:40 patients with Chlamydia psittaci pneumonia diagnosed at Jiangxi Provincial People’s Hospital from September 2019 to January 2023 were selected as the Chlamydia psittaci pneumonia group,40 patients with bacterial pneumonia during the same period were selected as the bacterial pneumonia group,28 patients with Mycoplasma pneumonia and 2 patients with Legionella pneumonia during the same period were selected as the other atypical pathogen pneumonia group,Compare the general situation,clinical symptoms,laboratory indicators,and imaging characteristics of the Chlamydia psittaci pneumonia group with the bacterial pneumonia group and other atypical pathogen pneumonia groups,and analyze the treatment and prognosis of Chlamydia psittaci pneumonia.Results:Compared with the bacterial pneumonia group,the group with Chlamydia psittaci pneumonia had a history of contact with poultry and birds,and the proportion of developing severe pneumonia was higher than that of the bacterial pneumonia group;The group with Chlamydia psittaci pneumonia developed fever,especially high fever(>39 ° C),with a higher proportion of overall soreness,weakness,headache,and relative bradycardia compared to the bacterial pneumonia group;The neutrophil percentage,D-dimer,glutamic acid transaminase,glutamic acid transaminase,creatinine,lactate dehydrogenase,C-reactive protein and interleukin-6levels in the chlamydia psittaci pneumonia group were higher than those in the bacterial pneumonia group,while the white blood cell count,lymphocyte percentage,albumin,sodium level were lower than those in the bacterial pneumonia group;The chest CT of Chlamydia psittaci pneumonia showed consolidation shadows,bronchial inflation signs,and a higher proportion of pleural effusion compared to the bacterial pneumonia group,while the proportion of ground glass shadows was lower than that of the bacterial pneumonia group.The above differences were statistically significant(P<0.05).Compared with other atypical pathogen pneumonia groups,the age,history of contact with poultry and birds,and the proportion of developing severe pneumonia in the Chlamydia psittaci pneumonia group were higher than those in the other atypical pathogen pneumonia groups;The group with Chlamydia psittaci pneumonia showed higher incidence of high fever and relative bradycardia compared to other atypical pathogen pneumonia groups;The percentage of neutrophils,glutamic transaminase,glutamic transaminase,creatinine,lactate dehydrogenase,C-reactive protein,procalcitonin,ferritin and interleukin-6 levels in the chlamydia psittaci pneumonia group were higher than those in other atypical pathogen pneumonia groups,while the percentage of lymphocytes,albumin and sodium levels were lower than those in other atypical pathogen pneumonia groups;The chest CT of Chlamydia psittaci pneumonia showed consolidation,bronchial inflation sign,and a higher proportion of pleural effusion compared to other atypical pathogen pneumonia groups,and the above differences were statistically significant(P<0.05).Treatment and outcome,Tigecycline combined with moxifloxacin was still ineffective after anti infection treatment,and septic shock and multiple organ failure occurred,and eventually died.Conclusion:1.Compared with other community-acquired pneumonia,patients with Chlamydia psittaci pneumonia are more likely to exhibit high fever,progress faster,and develop into severe pneumonia.Inflammatory markers,liver enzymes,creatinine,and lactate dehydrogenase levels are higher,while albumin and blood sodium levels are lower.2.In clinical practice,for CAP patients with poor efficacy in empirical anti infection treatment,m NGS testing of BALF should be performed as early as possible to clarify the etiology and provide guidance for clinical treatment.