The Correlation Between The Anatomy Of Bladder Neck And Benign Prostatic Hyperplasia Measured By Transrectal Ultrasound

Objective: In the present study,transrectal ultrasonography(TRUS)was used to measure the bladder neck Angle of benign prostatic hyperplasia(BPH)patients.BNA),to explore the correlation between the bladder neck anatomy and urinary flow rate and the severity of lower urinary tract symptoms(LUTS)in PATIENTS with BPH,and to investigate whether BNA can be used as a predictor of drug treatment efficacy in patients with BPH.Methods: Patients with BPH who first visited the First Affiliated Hospital of Jinan University from September 2020 to May 2021 were analyzed and followed up for one year after treatment.TRUS examination was performed in all patients,and all prostate anatomical parameters,residual urine volume,and urine flow rate after urination were measured.Patients were also scored according to International Prostate Symptom Score(IPSS)criteria before and after treatment.R 4.0.2 was used for statistical analysis of the data to study the correlation between the parameters.Results: A total of 401 patients were completely followed up,and multifactor linear regression analysis showed that BNA was independently correlated with peak flow rate(Qmax)and IPSS.The mean BNA of patients with severe LUTS was 84.1°,and that of patients with Qmax<10m L/s was 87.8°,both significantly higher than that of patients with mild BPH.Linear regression analysis showed that BNA was positively correlated with total IPSS(R= 0.721,P< 0.001)and negatively correlated with Qmax(R= 0.526,P< 0.001).BPH patients receiving drug therapy and patients with larger BNA have worse treatment effects.For BPH patients presented with acute urine residual(AUR),82.7% of patients with BNA greater than 89.4° were treated surgically for poor response to conservative treatment of AUR.Conclusion: BNA was significantly associated with LUTS and urinary flow rates in patients with BPH and could be used as a predictor of conservative treatment outcomes in patients with BPH.These results suggest that BNA may play an important role in the pathogenesis of BPH and AUR.