Study On The Intervention Effect Of Modified Yupingfeng Powder Combined With Breathing Exercise On GOLD1-2 Grade Stable COPD Patients

Objective:1.Through clinical observation of the effects of Jiawei Yupingfeng Powder combined with breathing exercises on TCM syndrome scores,CAT scores,inflammatory indexes,T lymphocyte subsets and lung function in GOLD1-2 grade stable COPD patients,and record the adverse reactions,the effects and advantages of Jiawei Yupingfeng powder combined with breathing exercises in the treatment of COPD were described,opening a new idea for the treatment of COPD.2.Provide reasonable and comprehensive treatment for GOLD1-2patients with COPD at stable stage,and provide scientific guidance for individual treatment of COPD.Methods:The final 120 patients with stable COPD were randomly divi ded into a conventional group: ICS/LABA therapy or LAMA inhala nt.Traditional Chinese medicine group: on the basis of the con ventional group treatment,added flavor Yupingfeng powder.Brea thing exercise group: On the basis of the conventional group t reatment,but also increased the breathing exercise training.C ombination group: On the basis of the conventional group treat ment,also added supplemented Yupingfeng powder and breathing exercise training therapy.After 3 months,TCM syndrome score,CAT score,inflammatory index,T lymphocyte subsets and lung f unction were observed and compared among all groups.Results:1.In terms of efficacy evaluation and TCM syndrome scores,the best group was the combination group.Although both the respiratory exercise group and the TCM group achieved some improvement,there was no statistical significance,and these three groups showed advantages compared with the conventional group.2.Clinical symptoms of traditional Chinese medicine: the combination group was the best,and each group was better than the conventional group.The traditional Chinese medicine group and the respiratory exercise group had different degrees of improvement,but there was no significant difference.3.CAT score: the combination group was the best,and all groups were better than the conventional group.No significant difference was found between the traditional Chinese medicine group and the respiratory exercise group.4.Improvement of inflammatory indexes: After intervention,IL-8 indexes in all groups were improved to varying degrees compared with those without intervention,and the combination group was the best,followed by the traditional Chinese medicine group,conventional group and respiratory exercise group.5.T cell subsets: After the intervention of CD8+ and CD4+/CD8+,both the Chinese medicine group and the combination group showed significant improvement,and the combination group had advantages over the Chinese medicine group,while the respiratory exercise group and the conventional group had no improvement.6.Lung function: After intervention,in terms of FEV1% and FEV1/FVC indexes,the combination group was significantly improved compared with the other three groups,while the conventional group,the traditional Chinese medicine group and the respiratory exercise group all had different degrees of improvement,but there was no statistical significance between them.Conclusion:1.The treatment of supplemented Yupingfeng Powder combined with respiratory exercise can more effectively improve the clinical symptoms of GOLD1-2 grade stable COPD patients,reduce airway inflammatory activity,enhance immune function,improve lung function,and promote the improvement of quality of life.2.The treatment of supplemented Yupingfeng Powder combined with respiratory exercise has good safety.