Summary Of Professor Li Xinmin’s Medication Rule In The Treatment Of Children’s Anaphylactoid Purpura And Its Correlation Analysis With Children’s Constitution

Objective:1.Analyze the prescription medication data of Professor Li Xinmin’s treatment of children with allergic purpura,and summarize the prescription medication ideas and prescription characteristics of Professor Li Xinmin.2.Analyze the correlation between allergic purpura and children’s physical factors,in order to provide a basis for the prevention and treatment of children with allergic purpura.Method:collect during November 2018 to February 2021,in the first affiliated hospital of Tianjin university of Chinese medicine pediatric outpatient service and inpatient by professor min-min li diagnosis and treatment of allergic purpura children 122 cases,using SPSS 26,SPSS Modeler 18 software for children collected clinical data,such as gender,age,season,cause,etc.,syndrome type,prescription drugs,etc as data statistics.The collected data was established by Excel database,preliminary statistics and information summary were conducted,and SPSS Staistics 26 was used for drug cluster analysis.Cluster analysis used systematic clustering method and Pearson method as the clustering method,and the results were represented by dendrogram;Use SPSS Staistics 26 to check-square test and SPSS Modeler 18 to display TCM association and analysis of Apriori algorithm.Results:1.General data:the sex distribution of allergic purpura has more boys than girls;the higher age is 5-12 years old;mainly in winter and spring;the most common cause is related to upper respiratory tract infection;high children with allergic history;and TCM syndrome type distribution.2.Physical distribution:Among the 122 children,100 were single constitution,accounting for 81.97%of the total number in this survey.The single constitution of 100 children with allergic purpura was 33(33.00%),17(17.00%),16(16.00%),15(14.00%),12(12.00%),sputum dampness 4(4.00%),2(2.00%),blood stasis 1(1.00%),and 1(1.00%).3.There was no significant correlation between the distribution of physical fitness type and gender(X~2=6.681,P=0.571>0.05);associated with the age of the child,the proportion of preschool age and peaceful quality is 41.67%,which will be significantly higher than the average level of 17.00%.The proportion of Yin deficiency matter at school age is43.55%,which will be significantly higher than the average level of 33.00%.The proportion of wet and humid quality in adolescence is 23.08%,which will be significantly higher than the average level of 14.00%;a correlation with onset season(P=0.034<0.05);and significant correlation with TCM syndrome(p<0.05).4.The frequency of drug use was 3245 times,involving 57 kinds of Chinese medicine(excluding licorice).Among them,there are 17 kinds of Chinese medicine with the frequency of more than 40%,according to the order of decreasing frequency is:bran fried aurantii,platycodon,white skin,skin,root,white grass,forsythia,scutablets,mint,honeysuckle,charcoal,small,fried burdock,reed root,isatidis,bran fried coix seed,cicada molting.The frequency of heat-clearing drugs was 1212 times,accounting for 37.35%of the total frequency;the frequency of hemostatic drugs was 480times,accounting for 14.79%of the total frequency.The solution drugs and phlegm,cough and asthma drugs were similar,13.28%and 12.91%,respectively.These four categories are the main drugs for the tutor to treat allergic purpura.5.Statistical analysis of 35 drugs with more than 10%use frequency showed the most cold drugs,accounting for 19 drugs54.29%;Next by warm 8,22.86%;flat 4,11.43%;cool 4,11.43%.Bitter taste drugs were the most frequent,with 20 occurrence frequency,accounting for 35.71%.Xin and sweet appeared 17and 12 times each,accounting for 30.36%and 21.43%respectively;The frequency of the above three drugs accounted for 87.50%.Many meridians belong to hand taiyin lung meridian,foot Yangming stomach meridian,foot yin spleen meridian,foot jue yin liver meridian,the cumulative frequency of use reached 73.50%.6.According to the cluster map,found C1:half branch lotus,white herb,ephedra,red peony,fried bark;C2:C3:white skin,skin,Xinjiang purple grass,mint,honeysuckle,charcoal,forsythia,small choke,white root;C4:reed root;C5:bran fried root,dried root,C6:Zhejiang,purple flower,lotus root;C7:six divine fruit,Huoxiang,half summer,ginger,Poria,tangerine peel,coix seed;C8:fairy crane,raw gypsum and other 8 groups of drugs.conclusion:1.Children with allergic purpura are more men than women,with the most onset age of school age,high incidence in winter,spring and autumn,and more common history of allergy.Infection factors are common in respiratory tract infection,and the distribution of TCM syndrome type is mostly wind heat syndrome and blood fever syndrome.2.Professor Li Xinmin has obtained the treatment characteristics of children’s allergic purpura:Based on the classical theory and the physiopathological characteristics of children,we pay attention to viscera syndrome differentiation,especially lung and spleen,clearing heat and blood,regulating the spleen and stomach,regulating the liver and spleen,and restoring the physiological functions of the viscera organs;light and flexible prescriptions,antipyretic drugs,hemostasis drugs,phlegm,cough and asthma medicines as high-frequency medicines.3.Physical Identification Results of Traditional Chinese medicine,Yin deficiency quality,peaceful quality,qi deficiency quality,hot and humid quality and special quality were the main physical types,and physical fitness had no significant correlation with gender factors,but with the age of onset,season of onset and type of TCM syndrome.