Study On The Syndromes Analysis And Drug Use Rules Of Post-infection Cough Treated By Professor Li Xinmin

Objective: To analyze and discuss the syndrome differentiation and types of children’s post-infection cough,and to summarize Professor Li Xinmin’s prescriptions and medication rules in the treatment of children’s post-infection cough,as well as his thinking and academic thought.METHODS: Cases of post-infection cough treated by Professor Xinmin Li were collected from the Pediatric Outpatient Department of the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine between April 2019 and February 2021.To collect the syndromes,treatments,complete prescriptions,clinical manifestations and other information of children with post-infection cough that meet the standards.Input and summarize the data with Excel,establish a complete database,and use SPSS 21.0 and SPSS Modeler statistical system to conduct data analysis and discussion on general information,syndrome differentiation,medication rules and other aspects,summarizing Professor Li Xinmin’s thought of syndrome differentiation and clinical experience in treating infantile post-infection cough.Results: Statistical analysis showed that the age of onset was mainly between 1 and 7years old.The most common syndromes were wind-heat invasion of the lung syndrome,followed by phlegm-heat obstruction of the lung.The other syndromes in descending order were: wind-evil invasion of the lung syndrome and phlegm-dampness accumulation syndrome.Summarized Professor Li Xinmin’s commonly used drug pair and drug combination in the treatment of children with post-infection cough,and summarized the relevant treatment prescriptions,including the addition and subtraction of Zi Su powder cutting,Ma Xing Shi Gan Tang cutting,Xing Su powder cutting,Er Chen Tang cutting,Su Ting pill cutting,etc.Based on professor he make a diagnosis and give treatment children with post-infection cough prescription medication after statistical analysis,inductive use frequency is not less than 5% of the commonly used traditional Chinese medicine(TCM)has a Glycyrrhiza glabra,Radix Platycodon grandiflorum,Fried Citrus aurantium shell,Zhaobei mother,Bitter almonds,Scutellaria baicalensis,Qingxia hemihot,Aster,Radix eucommiae,Chen Pi,Su Zi,Mulberry bark,Honey ephedra,Scapularia scopariae,Loquat leaf,Raw gypsum,etc.Among them,the efficacy of commonly used drugs is mainly distributed in the phlegm,cough and asthma medicine,heat-clearing medicine,qi-regulating medicine,antiphlogistic medicine,and deficiency medicine;the medicine is warm and cool and calm,with no obvious deviation in medicinal properties,and the bitter,pungent and sweet-tasting drugs are parallel,with bitter and pungent-tasting drugs being the dominant ones;the drugs belong mainly to the lung meridian,followed by the stomach,spleen,heart,bladder,large intestine,liver,small intestine,kidney and gall bladder meridians.The association rule analysis of traditional Chinese medicine with the use frequency of more than 5%(excluding licorice)showed that the 27 groups with the highest percentage of rule support were obtained,among which 6 groups with relatively high degree of support,confidence and gain were Radix Platycodon grandiflorus-fried hedgehog;Radix Platycodon grandiflorus-zhebeijia and fried hedgehog;Scutellaria baicalensis-radix platycodon and fried hedgehog;bitter almond-radix platycodon and fried hedgehog;zhebeijia-apricot;zhebeijia-bitter almond.Cluster analysis was carried out on the traditional Chinese medicines with the use frequency of more than 5%(excluding licorice),and 6 commonly used drugs were summarized: Cicada-Burdock,Qian Hu-Bai Qian,Jin Yin Hua-Lian Qiao,Jin Yin Hua-Mint,Ma Huang-Su Zi,and Mandarin-Fried Hovenia.Summarize 6 kinds of commonly used drug combination:C1 Scutellaria baicalensis,Psidium guajava,Phellodendron zhejiangensis,fried Citrus aurantium,Pericarpium citriodora,Platycodon grandiflorum,Glycyrrhiza glabra,Bacopa monnieri,Aster,Su Zi,Morinda citrifolium,C2 Forsythia,Peppermint,Echinacea purpurea,Tempeh,Platycodon grandiflorum,Panax quinquefolium,Rutabaga,Cicadellia,Burdock seed,Honeysuckle,Glycyrrhiza glabra;C3 Su Ye,Poria,Bai Qian,Qian Hu,Bitter Almond,Qing Han Xia,Hou Pu,Licorice,Di Long,Mandarin,Fried Citrus Aurantium;C4Chen Pi,Honey Ephedra,Su Zi,Scapularia,Loquat Leaf,Psidium Guajava,Mulberry Bark,Raw Gypsum,Bitter Almond,Qing Han Xia,Licorice;C5 Mandarin,Scutellaria,Fried Citrus Aurantium,Bai Mao Root,Bai Bai Bai,She Gan,Aster,Chen Pi,Bai Qian,Licorice;C6Honey Ephedra,Su Zi,Psidium Guajava,Mulberry Bark,Raw Gypsum,Scapularia,Loquat Leaf,Bitter Almond,Licorice.Conclusion: The cases included in this study include four syndrome types of post-infection cough:wind-heat attacking the lung,phlegm-heat congestion of the lung,wind-cold attacking the lung,and phlegm-dampness containing the lung.Through the analysis and study of syndrome types and statistical analysis of drugs from different perspectives,the author obtained Professor Li Xinmin’s thought of syndrome differentiation and treatment and clinical experience in the treatment of post-infection cough in children.Professor Li Xinmin,guided by the classical theory of traditional Chinese medicine and combined with clinical practice,focuses on the physiological and pathological characteristics of children,especially the deficiency of spleen in children.In the clinical treatment of post-infection cough in children,it is advocated to give priority to differentiation of viscera,especially lung and spleen;Emphasis on symptomatic treatment,divided into treatment,the treatment methods includes promoting the lung and removing wind,clearing heat and stopping cough;removing wind and dispersing cold,promoting the lung to dispel evil;drying dampness and strengthening the spleen,resolving phlegm and stopping cough;clearing heat and resolving phlegm,promoting the lung to stop cough,etc.He always pay attention to care for the spleen and stomach,transporting the spleen and strengthening the spleen to restore the physiological functions of the viscera,prescription light and flexible,there are main times.