| Purpose:In this study,by observing the effect of Nourishes Yin Hidroschesis Decoction on the clinical symptoms of patients with yin deficiency and fire-prosperity type sweat syndrome,we evaluated its efficacy and explored the mechanism of action.In order to provide new ideas for clinical treatment of Yin deficiency and fire-prosperous sweat syndrome.Method:A total of 68 patients with sweat syndrome who met the relevant diagnosis and inclusion criteria of traditional Chinese medicine and Western medicine were collected from January 2021 to December 2021 in the internal medicine outpatient department of Shanxi Provincial Hospital of Traditional Chinese Medicine.groups,34 cases in each group.The experimental group was treated with self-made Nourishes Yin Hidroschesis Decoction orally,and the control group was treated with Danggui Liuhuang Decoction orally.4 weeks is a course of treatment.The indicators of the two groups were observed and recorded before and after treatment,and the clinical efficacy and safety of the main symptoms of sweating and the concurrent symptoms of traditional Chinese medicine were evaluated.According to the changes of anxiety and symptoms before and after treatment combined with multi-factor correlation analysis,to explore whether anxiety factors affect the main symptoms of sweating.Statistical software SPSS26.0 was used for data statistics and analysis of the data obtained from the experiment.Result:1.Safety evaluation: no adverse reactions related to taking the drug occurred in the case during the trial.2.Comparison of the curative effect of the main symptoms of sweating: There was no statistical difference in the scores of the quantitative score table for the main symptoms of sweating between the two groups before treatment(P>0.05).After 4weeks of treatment,the total scores of the main symptoms of sweating in both groups were decreased(P < 0.05),and the total scores of the main symptoms of the experimental group were significantly lower than those of the control group(P < 0.05).After the course of treatment,the overall effective rate of the experimental group was higher than that of the control group(P<0.05).3.Comparison of the efficacy of TCM concurrent symptoms: There was no statistical difference in the single score of TCM concurrent symptoms of 7 items of yin deficiency and fire prosperous syndrome before treatment between the two groups of patients,such as soreness and weakness of the waist and knees,five heart upsets,dry mouth and throat,dizziness,tinnitus,bone evaporation heat,and insomnia(P >0.05).After treatment,the above 7 points in both groups were decreased(P<0.05).The above-mentioned five symptom scores in the experimental group were significantly lower than those in the control group(P<0.05).The symptom score of evaporative fever in the experimental group was higher than that in the control group,and the score of Wuxinfan fever was lower than that in the control group,and the difference was not statistically significant(P>0.05).After treatment,the total score of TCM comorbidity quantitative score scale in both groups was significantly decreased(P<0.05).The total score of the experimental group was lower than that of the control group(P<0.05).After the course of treatment,the overall effective rate of the experimental group was higher than that of the control group(P<0.05).4.Comparison of anxiety and disorder scores: before treatment,there was no significant difference in anxiety and disorder scores between the two groups(P>0.05),and after treatment,the scores of the two groups were both decreased,the difference in the scores of the experimental group was P<0.05,and the difference of the scores of the control group was P > 0.05.The anxiety and syndrome scores of the experimental group were significantly lower than those of the control group,P<0.05,and the difference was statistically significant.5.Correlation analysis between sweating evidence and anxiety syndrome: The severity of sweat evidence was not significantly related to gender,age,sweating course,nature of work,work pressure and place of residence.The severity of irregular work and rest and the degree of anxiety were significantly associated with the aggravation of sweating.The severity of anxiety was not significantly correlated with age,sex,duration of sweating,nature of work,financial stress and place of residence,but was significantly associated with the severity of work stress and sweating and the severity of anxiety complications.Conclusions:1.Nourishes Yin Hidroschesis Decoction is clinically effective in treating the main symptoms of yin deficiency and fire exuberance type sweat syndrome,and its curative effect is better than that of the control group Danggui Liuhuang Decoction.2.Nourishes Yin Hidroschesis Decoction can effectively improve the symptoms of traditional Chinese medicine and related anxiety symptoms such as soreness and weakness of waist and knees,five heart upsets and heat,dry mouth and throat,dizziness,tinnitus,bone evaporation fever,etc.The curative effect is better than that of the control group.3.Nourishes Yin Hidroschesis Decoction is effective,advantageous and safe in the treatment of yin deficiency and fire-prosperous sweat syndrome. |
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