| Objective:This study was to observe the improvement of nasopharyngeal mucosal thickness,nasopharyngeal secretion,nasopharyngeal mucosal congestion and swelling,pharyngeal lateral cord swelling,nasopharyngeal aspiration,pharyngeal pain,pharyngeal dryness and pharyngeal itching symptoms of Tongqiao Xuanbi Decoction in the treatment of children with chronic nasopharyngitis(phlegm and blood stasis type).To verify its efficacy and explore its safety.Methods: Selected since October 2020 to March 2021 in heilongjiang university of Chinese medicine and the first affiliated hospital of pediatrics 2families clinics in chronic nasopharyngitis(for inexpensive mutual junction)into the standard to carry on the research into the group,80 cases,son of the conform to the standards in accordance with the subjective intend to,children and their parents,were divided into experimental group(n=40)and in control group(n=40).The experimental group took Tongqiao Xuanbi Decoction orally,and the control group took Nasopharyngeal Qingdu granule orally.The treatment course was 3 weeks.Symptom scores of the two groups were statistically analyzed before treatment,1,2 and 3 weeks after treatment.Lateral nasopharyngeal film/Nasopharyngeal CT examination was performed before and after treatment,and the thickness of nasopharyngeal mucosa was recorded and changes of nasopharyngeal mucosa were observed before and after treatment.Results:1.Analysis of total curative effect: the total effective rate of the experimentalgroup in improving symptom and sign volume was 89.47%,which was significantly higher than that of the control group(72.97%),and the difference was statistically significant(P<0.05).The effect was more significant in children than in the control group.2.Comparison of TCM syndrome scores and signs: After 1,2 and 3weeks of treatment,the total scores of Tongqiao Xuanbi Decoction group were significantly lower than those of the control group,The difference was statistically significant(P< 0.05),It shows that Tongqiao Xuanbi Decoction group has a faster effect on children with chronic nasopharyngitis(phlegm and blood stasis type),and the effect is better than that of the control group.The experimental group was better than the control group in the improvement of partial secretion of nasopharynx,thickness of nasopharynx mucosa,congestion and swelling of nasopharynx mucosa,swelling of pharyngeal lateral cord,nasopharynx aspiration,pharyngeal dryness and pharyngeal itching(P<0.05);For the symptoms of pharyngeal pain,the curative effect of the control group was equivalent to that of the experimental group(P>0.05).3.Comparison of the thickness of nasopharyngeal mucosa: there was significant difference between the experimental group and the control group before and after treatment(P<0.05),indicating that they can reduce the thickening of nasopharyngeal mucosa;There was significant difference between the groups after treatment(P<0.05).The thickness of nasopharyngeal mucosa in the experimental group decreased more significantly,indicating that the experimental group was more effective in reducing the thickening of nasopharyngeal mucosa.4.Comparison of recurrence rate: after 3 months of follow-up,the recurrence rate of the experimental group was 5.88% and that of the control group was 29.63%.In comparison,the recurrence rate of the experimental group was lower than that of the control group,and Tongqiao Xuanbi decoction had better curative effect.The difference was statistically significant(P<0.05).Conclusion:1.The treatment of chronic nasopharyngitis(phlegm and blood stasis interaction type)by Tongqiao Xuanbi Decoction has a quick effect,with significant clinical effect.2.Tongqiao Xuanbi decoction can effectively improve the symptoms of nasopharyngeal secretion,pharyngeal lateral cord swelling,nasopharyngeal aspiration,sore throat,dry throat,pharyngeal itching,congestion,thickening and swelling of nasopharyngeal mucosa in children with chronic nasopharyngitis(phlegm and blood stasis type).3.Tongqiao Xuanbi decoction can reduce the recurrence rate of children with chronic nasopharyngitis in a short time. |
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