Retrospective Analysis Of Yangxin Zhitong Decoction In Treating Stable Angina Pectoris Of Coronary Heart Disease (Qi Deficiency And Blood Stasis Syndrome)

Objective:By means of retrospective analysis,the general situation and characteristics of stable angina pectoris of coronary heart disease(Qi deficiency and blood stasis syndrome)were analyzed,and professor Zhou Yabin’s experience in treating this disease with Yangxin Zhitong Decoction was summarized,providing ideas and medication guidance for clinical treatment.Methods:The patients with stable angina pectoris of coronary heart disease(Qi deficiency and blood stasis syndrome)treated by Yangxin Zhitong Decoction were found in professor Zhou Yabin’s outpatient electronic medical record system.A total of 163 patients were screened out as the research objects.The relevant data of the patients were classified and recorded in Excel,and analyzed by SPSS26.0,and the conclusions were drawn.After extracting and standardizing the relevant data of the included patients,a database was established and analyzed through the TCM inheritance auxiliary platform to summarize professor Zhou Yabin’s medication experience in treating stable angina pectoris of coronary heart disease(Qi deficiency and blood stasis syndrome).Results:1.Morbidity characteristics: There were more male patients included in this study,male: female ratio was 1.2:1;The lowest age was 40 years old,the highest age was 87 years old,60-69 years old was the most,accounting for 44.79%.The incidence season was most in winter,accounting for 33.7%.The course of disease was more than 10 years,accounting for 34.97%.Hypertension was the main complication,and 136 patients had hypertension,accounting for 83.43%.2.Symptoms: The symptoms with high frequency in the patients included in this study were chest pain,chest tightness,shortness of breath,fatigue,aggravation after activity,back pain,insomnia,spontaneous sweating and palpitations.The highest frequency of tongue image was light red,the highest frequency of tongue coating was thin,and the highest frequency of pulse pulse was heavy and thin.3.Blood pressure: In the patients included in this study,the systolic blood pressure was 156.30 ± 16.31 mm Hg before treatment and 134.33 ± 10.89 mm Hg after treatment;The diastolic blood pressure was 94.00 ± 13.42 mm Hg before treatment and 80.58 ± 5.94 mm Hg after treatment.The blood pressure values before and after treatment were analyzed by paired sample T test,and the differences were statistically significant(P<0.05),and significantly decreased after treatment.4.Myocardial enzyme status: Among the patients included in this study,CK was 178.76±17.40(U/L)before treatment and 103.26±10.18(U/L)after treatment;CK-MB was 15.94±2.74(U/L)before treatment and 9.06±1.68(U/L)after treatment.LDH was 280.49±32.05(U/L)before treatment and184.40±21.36(U/L)after treatment.The three myocardial enzymes before and after treatment were analyzed by paired sample T test,and the differences were statistically significant(P<0.05),and significantly decreased after treatment.5.Blood lipid: TC of the patients included in this study was6.074±0.917mmol/L before treatment and 5.316±0.846mmol/L after treatment;TG was 2.137±0.530mmol/L before treatment and 1.909±0.344mmol/L after treatment.LDL was 3.857±0.802mmol/L before treatment and3.485±0.877mmol/L after treatment.HDL was 0.905±0.228mmol/L before treatment and 1.009±0.316mmol/L after treatment.T test of paired samples before and after treatment showed significant differences(P<0.01).TC,TG and LDL decreased significantly after treatment,while HDL increased significantly after treatment.6.Analysis results of common drugs: the drugs with the highest frequency were tonifying deficiency,promoting blood circulation and removing stasis,resolving phlegm,relieving cough and relieving asthma,benefiting water infiltration and dampness and tranquilizing nerves,835 times,419 times,330 times,306 times and 228 times,respectively.7.Analysis of the four Qi and five flavors of commonly used drugs: the frequency of mild and flat drugs was the most,1028 times and 995 times,respectively;The number of times of sweet medicine was 1871,the number of times of bitter medicine and spicy medicine was 1097 and 1079,respectively.The number of drugs belonging to lung meridian and heart meridian was 1693 and 1616,respectively.Conclusion:1.In this study,the incidence of CHD stable angina pectoris(Qi deficiency and blood stasis syndrome)was higher in males than in females,the onset season was more common in winter,the onset age was more common in 60-69 years,the course of disease was more common in more than 10 years,and the associated diseases were more common in hypertension.2.Yangxin Zhitong Decoction can obviously improve the blood pressure level,myocardial enzyme level and blood lipid of patients with stable angina pectoris of coronary heart disease(Qi deficiency and blood stasis syndrome).3.Professor Zhou Yabin treats stable angina pectoris of coronary heart disease(syndrome of Qi deficiency and blood stasis)with nourishing and dispelling evil as the fundamental method.He often takes warming drugs,invigorating blood and removing stasis drugs,reducing phlegm,calming drugs and returning to spleen meridian as his adjuvant drugs,nourishing and dispelling evil and taking into account the five zang organs.