Study On The Distribution Characteristics Of Tcm Syndrome Elements And Its Correlation With Serum Ferritin In Patients With Perimenopausal Hypertension

Objective:The aim of this study was to record and organize the clinical data of perimenopausal hypertensive patients,to summarize the distribution characteristics of TCM syndrome elements in this population,and to statistically analyze the relationship between syndrome elements of disease proportion and risk factors,serum ferritin,in order to provide some ideas and basis for the management of perimenopausal hypertension in TCM.Methods:The case source was 124 perimenopausal hypertensive patients from First Affiliated Hospital of Heilongjiang University of Chinese Medicine,and the general information,observation of clinical symptoms and the collection of blood pressure,serum ferritin(SF),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),lipoprotein(a)[Lp(a)],and body mass index(BMI)were collected by means of an information questionnaire.Excel sheet for summarizing the evidence information by referring to the syndrome elements scale in Syndrome elements-based Identification,after integrating the data,SPSS 26.0 software was used to conduct the analysis of the distribution characteristics of the evidence elements,statistical methods such as univariate analysis and binary logistic regression analysis were used for correlation analysis of risk factors.Results:1.Syndrome elements of disease position:liver(52.23%)>heart(30.65%)>kidney(25.8%)>spleen(3.23%)>half table=half lung(0.81%);single disease position(49.1 9%)>double disease position(29.0 3%)>no disease position(19.35%)>three disease position(2.42%);all combinations of syndrome elements of disease position(including single disease location)were dominated by liver(25.00%),heart(13.71%),liver+kidney(12.10%),liver+heart(11.29%),and kidney(8.8 7%).2.Syndrome elements of disease proportion:phlegm(67.74%)>hyperactivity(33.06%)>blood stasis(32.26%)>dampness(31.45%)>qi stagnation(16.1 3%)for solid syndrome elements,yin deficiency(39.52%)>qi deficiency(39.52%)>qi deficiency(29.0 3%)>blood deficiency(12.90%)=Yang deficiency(12.90%)for deficient syndrome elements;double disease proportion(35.48%)>triple disease proportion(31.45%)>quadruple disease proportion(20.16%)>single disease proportion(8.87%)>quintuple pathology(4.03%);among all combinations of syndrome elements of disease proportion(including single disease proportion),the combination of deficiency and solid mixed syndrome elements(48.3 9%)>solid combination(40.3 2%)>deficiency combination(11.29%);phlegm(4.03%)and blood stasis(3.23%)for single disease proportion,yin deficiency+hyperactivity(7.27%),phlegm+hyperactivity(5.65%),phlegm+dampness(4.84%)for double disease proportion,phlegm+hyperactive yang+damp(5.65%),phlegm+blood stasis+damp(4.84%),and yin deficiency+hyperactive yang+other(8.06%)for triple disease proportion,qi deficiency+phlegm+damp+other(7.27%),qi deficiency+yang deficiency+blood stasis+other(4.0 3%)for quadruple and more disease proportion.3.Correlations between syndrome elements of disease proportion and risk factors:(1)age,TG,and BMI were positively correlated with phlegm;(2)the presence of combined diabetes was positively correlated with yin deficiency,and BMI was negatively correlated with yin deficiency.(3)Age was positively correlated with blood stasis;(4)Qi stagnation was negatively correlated with blood pressure class;(5)Dampness was positively correlated with BMI.4.Differences in TG and BMI in the comparison of concurrent syndrome elements:(1)In the comparison of the combination of solid syndrome elements and deficiency syndrome elements,the higher the TG value,the more the diagnosis of the syndrome elements tends to the combination of solid syndrome elements;(2)In the comparison of the combination of deficiency and solid mixed syndrome elements,the higher the BMI value,the more the diagnosis tends to the combination of deficiency and solid syndrome elements;in the comparison between the combination of solid syndrome elements and deficiency syndrome elements,the higher the BMI value,the more the diagnosis tends to the combination of solid syndrome elements.5.The SF level of menopausal patients was higher than that of non-menopausal patients,and the difference between the two groups was statistically significant;BMI and SF were positively correlated;patients with combined cerebrovascular disease SF levels tended to be higher in the higher group,and the difference between the two groups was statistically significant.Conclusion:1.Syndrome elements of disease position are mostly liver,heart,liver+kidney,liver+heart and kidney(in order of proportion).2.Syndrome elements of disease proportion are mostly solid mixed with deficiency and solid,with yin deficiency+hyperactivity+other,yin deficiency+hyperactivity,qi deficiency+phlegm+dampness+other,phlegm+hyperactivity,and phlegm+hyperactivity+dampness being the most common types(in order of proportion).3.The older the patient,the more the diagnosis tends to be phlegm and blood stasis;the higher the TG,the more the diagnosis tends to be phlegm and solid syndrome elements;the higher the BMI,the more the diagnosis tends to be phlegm,damp,solid syndrome elements or mixed syndrome elements of deficiency and solid,the less the diagnosis tends to be yin deficiency;the higher the blood pressure level,the less the diagnosis of evidence tends to be qi stagnation.4.SF level of menopausal patients is higher than that of non-menopausal patients;the higher the BMI,the higher the SF level;SF level of patients with combined cerebrovascular disease is higher than that of patients without combined cerebrovascular disease.