Objective:To observe the clinical efficacy of bushenhuoxue decoction combined with ultraso und-guided nerve block in the treatment of osteoarthritis of the knee with liver and ki dney deficiency,and to provide new ideas and methods for the clinical treatment of o steoarthritis of the knee.Methods:Seventy patients who met the inclusion and exclusion criteria for knee osteoarthrit is with liver and kidney deficiency in the Department of Orthopedics of Fuzhou Hospi tal of Traditional Chinese Medicine affiliated to Fujian University of Traditional Chine se Medicine from January 2021 to January 2022 were selected.Numbers were given a ccording to the order of treatment,and SPSS26.0 was used for simple random groupin g,which was divided into experimental group: Bushenhuoxue Decoction combined wit h ultrasound-guided nerve block treatment,and control group: ultrasound-guided nerve block treatment,35 cases in each group.Both groups received basic treatment includin g patient education and instruction of functional exercise.Two groups of nerve block once a week,1 course of treatment,treatment of 4 courses.The experimental group was treated with 4 courses of TCM Bushen Huoxue Decoction,one dose per day for5 days.And the patients were evaluated before treatment,after 2 weeks of treatment,and after 4 weeks of treatment in terms of TCM evidence score,WOMAC score and joint mobility,and the data were analyzed by applying SPSS26.0.Results:1.There were no statistical differences in gender,age,BMI and disease duration between the two groups(P > 0.05),which were comparable.There were no significan t differences in WOMAC pain score,WOMAC stiffness score,WOMAC somatic funct ion score,joint mobility,and quantitative Chinese medicine evidence grading score bef ore treatment between the two groups(P > 0.05),which were comparable.2.The WOMAC(pain,stiffness,and somatic function)scores were lower in bothgroups after 2 weeks and 4 weeks of treatment than before treatment(P < 0.05),an d the differences were statistically significant,suggesting that both groups had certain efficacy in improving joint pain,joint stiffness,and somatic function.The WOMAC(p ain,stiffness,and somatic function)scores of the test group were lower than those ofthe control group after 2 weeks and 4 weeks of treatment(P < 0.05),and the differ ence was statistically significant,suggesting that the test group was better than the co ntrol group in improving joint pain,joint stiffness,and somatic function.3.The joint mobility was higher in both groups after 2 weeks of treatment and a fter 4 weeks of treatment than before treatment(P < 0.05),which was statistically diff erent,suggesting that both groups could improve the knee joint mobility,and the kneejoint mobility was higher in the test group than in the control group after 2 weeks o f treatment and after 4 weeks of treatment(P < 0.05),which was statistically different,suggesting that the test group was better than the control group in improvingthe knee joint mobility.4.In both groups,the quantitative TCM classification scores were lower after 2weeks of treatment and after 4 weeks of treatment than before treatment(P < 0.05),a nd the difference was statistically significant,suggesting that both treatment groups we re effective in improving the TCM classification scores.The difference was statisticallysignificant,suggesting that the test group was better than the control group in terms of the efficacy of the Chinese medicine symptoms.5.The results of the study showed that there were 2 cases(5.7%)of clinical con trol,21 cases(60.0%)of significant effect,9 cases(25.7%)of effective effect and 3cases(8.5%)of ineffective effect in the test group,with an overall effective rate of 91.4%.In the control group,there were 0 cases of clinical control,8 cases of significa nt effect(22.8%),20 cases of effective effect(57.1%),and 7 cases of ineffective effe ct(20.0%),with a total effective rate of 80.0%,and the difference was statistically si gnificant(P<0.05).It suggested that the test group was better than the control group i n terms of comprehensive clinical efficacy.Conclusions:Bushenhuoxue decoction combined ultrasound guided nerve block and ultrasound guided nerve block two kinds of treatment of liver and kidney deficiency knee osteoarthritis are effective,but bushenhuoxue decoction combined ultrasound guided nerve block have better curative effect,it can alleviate symptoms of joint pain,stiffness,improve the joint activity,high safety and less adverse reaction. |