Study On The Risk Factors Of Thyroid Nodules And The Distribution Law Of TCM Syndrome Types

Objective: To understand the risk factors of thyroid nodules,to explore the distribution of TCM syndrome types in thyroid nodules,to initiate individualized interventions for thyroid nodules early,and to provide certain data support for the selection of clinical TCM diagnosis and treatment methods.Methods: According to the TI-RADS classification of thyroid nodules,the patients who met the inclusion criteria were divided into group A(TI-RADS1,2,3),B(TI-RADS 4a,4b,4c),and C(TI-RADS 4a,4b,4c).RADS 5,6).Filling in the thyroid nodule risk factor quantification form,the TCM syndrome collection form and the thyroid nodule basic information form,and use statistical analysis software for statistical processing.Results:1.Risk factor analysis: With nodule classification as the dependent variable,univariate ordinal regression analysis showed that eating habits,work and rest habits,emotional stress,smoking,drinking,BMI,family history,glucose and lipid metabolism,thyroid function,place of birth and current residence would all affect the nodule category,with statistical significance(P<0.05);Multivariate ordinal regression analysis showed that gender,eating habits,work and rest habits,emotional stress,smoking,drinking,family history,glucose and lipid metabolism,thyroid function and current residence all affected the nodule category,with statistical significance(P<0.05).2.Distribution of TCM syndrome types: Among the 144 patients included,Qi stagnation and blood stasis syndrome,phlegm and blood stasis syndrome,internal phlegm-dampness syndrome,and qi-yin deficiency and blood stasis syndrome are the most numerous syndrome types,and only in Age,age stratification,BMI,glucose and lipid metabolism,and thyroid function were statistically significant(all P<0.05).The average age of each syndrome type was 39±13.22 years old,40.77±14.26 years old,48.57±10.69 years old,60.82±12.07 years old,47.88±8.40 years old,the difference was statistically significant(P<0.01);Syndrome type and Qi-yin deficiency with blood stasis syndrome were the most common syndrome types among the three age groups,and the difference was statistically significant(P<0.01).Intrinsic syndrome,the difference was statistically significant(P<0.01);nodules with abnormal glucose and lipid metabolism were mostly phlegm and blood stasis syndrome,and nodules without glucose and lipid metabolism problems had the most other syndromes,and the difference was as follows: Statistical significance(P=0.002);the patients with other syndromes and qi stagnation and blood stasis syndrome are the most common in the normal thyroid function population,and the phlegm and blood stasis syndrome is the most common syndrome type in the abnormal thyroid function population,and the difference is statistically significant(P=0.037).Conclusion:1.The formation of thyroid nodules is related to factors such as environment,diet,mood,genetics,etc.This study further confirmed that gender,eating habits,work and rest habits,emotional stress,smoking,drinking,family history,glucose and lipid metabolism,thyroid function and current residence and other factors all affect the type of nodule.2.The TCM syndrome types of thyroid nodules are the most common four types:Qi stagnation and blood stasis syndrome,phlegm and blood stasis syndrome,internal phlegm-dampness syndrome,and Qi-yin deficiency and blood stasis syndrome.Pathological factors are mainly phlegm-dampness,qi stagnation and blood stasis,Different syndrome types have different distributions in terms of age,BMI,glucose and lipid metabolism,and thyroid function,suggesting that although the same pathological factors are seen during clinical treatment,due to the different characteristics of patients’ age,BMI,glucose and lipid metabolism,and thyroid function,The mechanism and pathological progress are not completely consistent,and the same disease should be treated differently,and the treatment should be based on the root.