Correlation Between Intraoperative Hypothermia And Prognosis Of Patients With Muscle Invasive Bladder Cancer

Objective: A retrospective study of 77 MIBC patients undergoing RC in our hospital,the relationship between intraoperative body temperature and postoperative complications and prognosis,the purpose wasprovide assistance for clinical diagnosis and treatment.Methods:(1)77 patients with MIBC confirmed by pathology and RC were selected.(2)The patients were divided into experimental group(intraoperative body temperature < 36 ℃)and control group(intraoperative body temperature > 36 ℃).(3)Use Kaplan Meier method to draw overall survival curve,so as to the patients of MIBC TNM stage Ⅱ.Logistic regression analysis,Log-rank test,and Cox multivariate analysis were used to study the independent risk factors and survival curve differences of MIBC prognosis between patients whose surgical temperature drops and those whose temperature does not drop.Results:(1)The incidence of hypothermia was 54.5%.(2)Gender,age,ASA-PS grade,operation time,smoking,clavin Dindo,lymphatic invasion,TNM stage Ⅱ were not independent risk factors of intraoperative hypothermia(P > 0.05).TNM stage ⅡI,TNM stage IV and 12-month recurrence rate are independent risk factors of intraoperative hypothermia(P < 0.05).(3)Intraoperative hypothermia was not an independent risk factor for postoperative complications,such as intestinal obstruction,urinary tract infection,SSI and cardiovascular events(P > 0.05).(4)Age,gender,smoking,etc were not independent risk factors for prognosis,so as to ASA-PS(P >0.05),while intraoperative hypothermia,urinary diversion,clavin Dindo were independent risk factors,so as to lymphatic invasion(P < 0.05).(5)In TNM Ⅱ patients of MIBC,lymphatic invasion was an independent risk factor for overall survival(P <0.05),also applies to intraoperative hypothermia(P < 0.05).Conclusion:(1)The incidence of hypothermia is 54.5%.(2)Intraoperative hypothermia is an important prognostic factor for RC,especially for TNM Ⅱ patients.