| ObjectiveBy collecting and analyzing factors such as age,history of pregnancy and childbirth,menstrual history,blood type,size and location of myoma,clinical symptoms,treatment plan,tongue and pulse,TCM syndrome type and so on,summarize the correlation between uterine leiomyoma and various factors,and the constitution classification of uterine leiomyoma patients.Toprovide objective basis for diagnosis and treatment of uterine leiomyoma and make it more humanized and reasonable.MethodsFrom September 1st 2015 to January 31 st 2018,there were 2559 hospitalized patients who’s colour Doppler ultrasound examination resulted that uterine myoma can be seen in sonography,were selected from the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine.The complete clinical data of the patients were collected for retrospective analysis,and the age distribution,blood group distribution,clinical symptoms,selection of treatment scheme and classification of TCM physique syndrome types of uterine leiomyoma were discussed.The EXCEL software was used to build up the database,and the SPSS 20.0 software was for statistical analysis.Results1.In 2559 patients,under the age of 30,a total of 165 cases,accounting for 6.45% of the total number;31-40 of the 768 cases,accounting for 30.1%of the total number;41-50 years of age in 1203 cases,accounting for 47.01%of the total number;51-60 of the 300 cases,accounting for 11.72% of the total number;and more than 60 year old patients with myoma only in 123 cases,accounting for the total sample 4.81%.2.According to the time of finding uterine leiomyoma in patients,the course of disease was speculated.The course of disease was less than one year,there were 432 cases within 1-5 years,there were 944 cases within 6-10 years,there were 187 cases in 11-15 years,98 cases in 16-20 years and 39 cases in21-25 years.3.There were 837 cases with family history,1269 cases without family history and 453 cases with unclear family history.4.According to the blood type,there were 771 cases of blood type A and612 cases of type B and 195 cases of type O were classified according to blood type.5.There were 2208 cases of intramural myoma,231 cases of submucous myoma,99 cases of subserous myoma and 21 cases of broad ligament myoma.6.The relative factor of uterine leiomyoma type:(1)The relationship between age and uterine leiomyoma type was compared with the other two groups.The results showed that there were significant differences in the location distribution of uterine leiomyoma in different age groups.The age of submucous leiomyoma was earlier than that of intramural myoma and subserous myoma,but the age of subserous myoma was earlier than that of myoma of muscularis interwall and leiomyoma of broad ligament.(2)The relationship between different blood groups and types of uterine leiomyoma was analyzed by fisher accurate probability method.The results showed that the location of uterine leiomyoma in different types of patients was different,and submucous myoma was more common in type a blood group.The proportion of muscular-wall myoma and broad ligament myoma were 40.4% and 42.9% respectively,while subserous myoma occurred in ab type group(51.5%).7.(1)The relationship between age and the choice of surgical method was analyzed by the test of orthospsia.The results showed that there was significant difference between laparoscope hysteromyomectomy and the other groups(P < 0.05),and there was a significant difference between the two groups(P < 0.05).Abdominal hysteromyomectomy had statistical significance compared with the other four groups(P < 0.05),but there was no significant difference between laparoscopic hysterectomy and hysteroscopy,and there was significant difference between the other groups and the other groups(P < 0.05).There was no significant difference between the other groups.(2)The size and type of uterine leiomyoma were analyzed by fisher precise probability method.The results showed that the size of uterine leiomyoma and the type of uterine leiomyoma were statistically significant in the choice of operation mode.8.In 2559 cases,there were six types of tongue veins : red,dark red,pale red,pale white,dim and fat.(2)There were 8cases(6.68 %),87 cases(34.00 %),672 cases(26.26 %)and 39 cases(1.5 %).The damp-heat-stasis resistance is 99 cases(3.63 %),kidney-deficiency blood stasis >qi-stagnant blood stasis > phlegm-dampness-stasis resistance > damp-heat-stasis resistance.9.(1)The relationship between age and uterine myoma syndrome type was analyzed by the analysis of the relevant factors of TCM syndrome type: 1.The results showed that there was no statistical significance in the distribution of syndromes in patients of different ages.(2)Through chi-square test and analysis,the relationship between the course of uterine leiomyoma and TCM syndrome type was statistically significant,in which qi stagnation and blood stasis,dampness and heat stasis,phlegm dampness and stasis were relatively short,generally within 2 years.However,kidney deficiency and blood stasis were more common in patients with long course of disease.(3)The relationship between uterine leiomyoma types and TCM syndromes was analyzed by fisher accurate probability method.The results showed that the distribution of TCM syndromes of different types of leiomyoma was statistically significant.Conclusion1.The data of this study show that the highest incidence of uterine leiomyoma is 40-50 years old;the course of disease occurs within 10 years,especially 6-10 years.The distribution of blood group indicates that there are more patients with uterine leiomyoma.2.It was found that the most common type of uterine myoma was myometrial myoma,age,blood type and the type of uterine myoma were also correlated.3.The main surgical methods of uterine leiomyoma include laparoscopic hysteromyomectomy,laparoscopic hysterectomy,abdominal hysterectomy,abdominal hysterectomy and hysteroscopic hysterectomy.The choice of operation mode was related to patient’s age,type of myoma,and size of myoma.4.In this study,we can conclude four TCM syndromes: kidney deficiency and blood stasis syndrome,qi stagnation and blood stasis syndrome,phlegm and dampness stasis syndrome,damp-heat stasis syndrome.The incidence rate of kidney deficiency and blood stasis was the highest,about 52,followed by Qi stagnation and blood stasis,about 28.The syndrome types suggest that the basic pathogenesis of uterine leiomyoma is stagnation of blood stasis,followed by kidney deficiency.The distribution of TCM syndromes of uterine leiomyoma is related to the course of disease and the type of uterine leiomyoma. |
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