| Objective :To investigate the effect of Mongolian medicine chaganwurile of serum pepsinogen and gastrin expression in patients with chronic atrophic gastrtis(CAG),and hope to provide detailed information and original data for the clinical formulation.Methods :In this study,60 cases of chronic atrophic gastritis patients who met the inclusion criteria in the digestive department and wards of the International Monglian Hospital of Inner Mongolia Autonomous Region from January 2020 to December 2020 were collected and randomly divided into the observation group and the control group,the observation group with 31 patients and the control group with 30 patient.The observation group was given Mongolian medicine chaganwurile,a single dose of 15 tablets(3G),30 minutes warm water befor meals in the morning and evening,the control group was given wei mei su tablets,a single dose of 4 tablets(0.8g),30 minutes warm water after breakfast、 lunch and dinner.12 weeks is a course of treatment,Get a courses of treatment.And symptom scores of Mongolian medicine and empty stomach serum pepsinogen and gastrin detection were performed before and after treatment.Observe the effect of Mongolian medicine chaganwurile of serum pepsinogen 、gastrin expression and clinical symptoms.The data were analyzed and processed by SPSS software.Results : there was no significant difference in age,gender,clinical symptoms,serum pepsinogen and gastrin expression course of disease between the two groups before treatment(P > 0.05).(1)In the observation group,the total effective rate was 93.5%,and in the control group,the total effective rate was80%,there was no significant difference between the two groupst(P > 0.05).(2)The symptoms of two groups of patients before and after treatment were significantly improved,the difference was statistically significantlyt(P < 0.05).(3)After treatment,the symptoms of epigastric pain,epigastric burning,gas distention,nausea,belching,mouth bitterness and other symptoms were improved similarly in both groups,with no statistical significance(P > 0.05).The symptoms of postprandibular fullness and discomfort,early satiety and inappetence were compared between the two groups,and the differences were statistically significant(P < 0.05).(4)in the two groups before Ⅰand after treatment in patients with serum PG,G-17 horizontal comparison: PG after treatment,PGR,G-17 levels significantly,the difference was statistically significant(P < 0.05);Before and after treatment with ⅡPG level change is not obvious,there was no statistically significant difference(P > 0.05).(5)in the two groups after treatment PG Ⅰ,PGR,G-17 horizontal comparison,the level of serum PG Ⅰ,G-17,the difference was statistically significant(P < 0.05);There was no significant difference in PGR level(P > 0.05).Conclusion : Mongolian medicine chaganwurile can effectively improve the clinical symptoms and ultrasonic examination results of cholechen fever,and has no obvious adverse reactions. |
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