Clinical Observation On The Treatment Of Gastroesophageal Reflux Disease Caused By Stagnation Of Liver And Stomach By Soothing The Liver And Relieving Heat And Harmonizing The Stomach

Objective:In the course of the treatment of gastroesophageal reflux disease syndrome of heat stagnation in liver and stomach,the method of relieving liver and reducing heat and stomach is used.The clinical efficacy and recurrence rate were observed in this process.In conclusion,the application prospect of traditional Chinese medicine in the treatment of gastroesophageal reflux disease is discussed.Methods:A number of patients who met the traditional medical criteria of gastroesophageal reflux disease diagnosed by Western medicine and heat stagnation in liver and stomach were selected as the research subjects.The total sample size is80 cases.Divide them into groups at random according to random number grouping.The number of people in each group is equal.Design a kind of intervention as a comparison.The intervention method was oral Chinese patent medicine,namely Puyuan and stomach capsule.The other group of intervention drugs was Chinese herbal decoction.The preparation principle of the decoction is soothing the liver,purging heat and harmonizing the stomach.This group is the observation group.The duration of intervention was set at 8 weeks.During this period,the patient’s signs,symptoms and related examinations were observed,and the prescription is adjusted to suit the circumstances.Adverse reactions were also recorded.Patients were followed up 8 weeks after completion of treatment.All gastroscopic results and symptom scores during this process were collected.Evaluating and analyzing the efficacy and recurrence rate is the last step.Results:Among the patients included this time,there were 6 cases of shedding.Among them,36 cases were completed in the control group and 38 cases were completed in the observation group.After tracking and recording the patient’s indicators,some conclusions are drawn.1.There were no statistical differences in the general conditions of different groups,such as age,gender,course of disease,gastroscope before treatment and symptom scores(except epigastric distension).So the two groups can be compared,P>0.05.2.The results of gastroscopy have changed,under the action of intervention drugs.The change in both groups is improvement.If we compare the effective rate of gastroscope improvement between the two groups,we will find that the observation group is larger than the control group(100%>86.11%),P<0.05.3.After receiving the intervention,each group had the same result.It is a decrease in the score of TCM syndrome.It has statistical significance.This shows that both interventions are effective,~▲P<0.05.4.The epigastric distension scores of the two groups before treatment were statistically significant different,so the intervention results were not compared,P<0.05.There is not much difference in other symptoms,so the intervention results could be analyzed and compared,such as heartburn,acid reflux,epigastric burning pain,throat discomfort,mouth bitterness,sternal burning pain and discomfort,belching or regurgitation symptoms,P>0.05.5.The score for each symptom is collected.The symptoms of epigastric distension were not compared,and there was no difference in scores after treatment of symptoms of throat discomfort(~◆P>0.05).In addition,scores of other symptoms decreased;When they were compared,the reduction was better in the observation group(~★P<0.05).6.The total score of TCM syndrome is analyzed at the end.The results showed clinical improvement.In the observation group,2 cases were ineffective,3 cases were effective,21 cases were significantly effective,and 12 cases were cured;in the control group,6 cases were ineffective,24 cases were effective,2 cases were significantly effective,and 4 cases were cured.The total efficiency can be obtained by calculating these data.The indexes of the two groups were 94.74%and 83.33%in the observation group and the control group,respectively.As a result,the observation group had a better effect(P<0.05).7.After 8 weeks of drug withdrawal,the recurrence rate of the observation group was lower than that of the control group(5.56%<23.33%),and the difference was statistically significant(P<0.05).8.There were no abnormal changes in the safety indexes in the course of treatment in the two groups,such as blood and urine routine,liver and kidney function and electrocardiogram,etc.To a certain extent,this suggests that the method of soothing the liver and relieving heat and stomach is safe and reliable.Conclusion:In this observation,the method of soothing the liver and relieving heat and stomach can effectively improve the clinical symptoms and microscopic mucosal condition of gastroesophageal reflux disease with liver-stomach stagnation heat,and reduce the recurrence rate within 8 weeks to a certain extent.Therefore,this method has a wide application prospect in clinic.