Correlation Analysis Of Sputum Evidence Of Hypertension,Cardiovascular Disease Risk And Cardiovascular Prognosis Index In Patients With Hypertension

ObjectiveBy exploring the correlation between high blood pressure Chinese medicine sputum certificate points and cardiovascular risk and clinical indicators affecting cardiovascular prognosmation of hypertension,it provides a certain clinical basis for the early combination of Chinese and Western medicine to prevent and control hypertension.MethodsThis topic used cross-sectional research methods to collect patients with primary hypertension who were clearly diagnosed during hospitalization from January 2016 to September 2020 in the University City Cardiovascular Department of Central Hospital in Guangdong Province.A total of 386 patients who met the standards were included.Collect general clinical data of patients,and conduct a chinese medicine sputum certificate score and 10-year assessment of isoemia cardiovascular disease.The data were processed and analyzed by Epidata 3.1,SPSS22.0 and other software to clarify the correlation between high blood pressure Chinese medicine sputum certificate points and cardiovascular risk and clinical indicators affecting cardiovascular prognosmical index of hypertension.Results(1)There were no statistical differences in gender,hypertension classification,risk stratization of hypertension,smoking,drinking alcohol,cardiovascular family history and other combined diseases in the sputum and non-sputum evidence groups of hypertension(P>0.05);Significant differences in age between the two groups were observed(P<0.05);There was no difference in the distribution of disease duration between the two groups(P>0.05).(2)According to the 10-year risk stratification of cardiovascular disease in patients with hypertension,there was no significant difference in drinking history,family history of cardiovascular disease,TIA,atrial fibrillation and heart failure among the groups(P>0.05);There were significant differences in hypertension classification,hypertension risk stratification,smoking history,diabetes mellitus and retinopathy among the groups(P<0.05).There was a positive correlation between hypertension risk stratification and cardiovascular risk stratification(r=0.283,P<0.01),a positive correlation between smoking history and cardiovascular risk stratification(r=0.195,P<0.01),and a positive correlation between diabetes history and cardiovascular risk stratification(r=0.302,P<0.01),There was a positive correlation between retinopathy and cardiovascular risk stratification(r=0.106,P<0.05).(3)Chinese medicine sputum card integral and HDL-C were negatively related(P<0.05),Chinese medicine sputum card integral was positively related to TG,BMI,HCY,IVS,LVPW,HbAlc,cardiovascular absolute risk value(P<0.05),Chinese medicine sputum card integral was positively related to age,TC,LDL-C,LVED,LVPW,LVMI,IMT,Cr,eGFR(P>0.05);negative correlation between cardiovascular absolute risk values and eGFR(P<0.01),cardiovascular absolute risk values with age,BMI,HCY,IVS,LVED,LVPW,LVMI,IMT,Cr,HbAlc,TCM sputum certificate integrals were positively related(P<0.01),and there was no significant correlation between cardiovascular absolute risk values and TC,LDL-C,HDL-C,and TG(P>0.05).Conclusion(1)Phlegm syndrome is one of the important TCM syndrome elements of hypertension;The higher the classification and risk stratification of hypertension,the higher the risk of cardiovascular disease in 10 years;Smoking,diabetes mellitus,retinopathy and hypertension increase the risk of cardiovascular disease.(2)Clinically,the lower the HDL cholesterol;triglycerides,body mass index,homocysteine,chamber space thickness,left chamber back wall thickness,glycerin,cardiovascular absolute risk value of higher hypertension patients,TCM multiple syndromes of syndrome differentiation and phlegm.(3)Clinically,hypertensive patients with lower eGFR,older age,higher body mass index,homocysteine,interventricular septum thickness,left ventricular end diastolic diameter,left ventricular posterior wall thickness,left ventricular mass index,arterial intima-media thickness,serum creatinine,glycated hemoglobin,and sputum score of TCM were predisposed to cardiovascular disease.