Objective: To observe the changes of c-reactive protein,erythrocyte sedimentation rate,blood uric acid and clinical syndrome before and after treatment,and analyze the clinical efficacy and safety.Methods: Eighty patients with acute gouty arthritis of damp-heat accumulation type were randomly divided into treatment group(40 cases)and control group(40 cases).The treatment group was treated with Danggui Niantong Decoction combined with pricking blood and the control group was treated with celecoxib.C-reactive protein,ESR,uric acid,clinical symptom score,TCM syndrome score,immediate analgesic effect and pain visual analogue scale(VAS)were statistically analyzed before treatment,the third day and the seventh day after treatment.Results:1.After treatment,the immediate significant efficiency was 83.78% in the treatment group and 62.86% in the control group,the difference being statistically significant(P<0.05).The effect of the treatment group was better than that of the control group.2.There was no significant difference between the two groups before treatment(P>0.05),but there was significant difference in clinical symptom score,TCM syndrome score,VAS score,C-reactive protein,erythrocyte sedimentation rate and serum uric acid level on the 3rd and 7th day after treatment(P<0.05),and the decrease level on the 7th day was more obvious than that on the 3rd day.The clinical symptom score,TCM syndrome score,VAS score,C-reactive protein,erythrocyte sedimentation rate and serum uric acid level of the two groups on the 3rd and 7th day after treatment were compared,and the difference was statistically significant(P<0.05).The treatment group was superior to the control group on the 3rd and 7th day.3.After treatment,the total effective rate of the treatment group was 91.89%,and the total effective rate of the control group was 80.00%,the difference was statistically significant(P<0.05),the effect of the treatment group was better than the control group.Conclusions: Danggui Niantong Decoction combined with collateralspricking and blood-releasing method can effectively improve the TCM syndrome scores of patients with acute gout arthritis of damp-heat accumulation type,reduce the levels of C-reactive protein,erythrocyte sedimentation rate and blood uric acid,which is worthy of clinical application. |