Clinical Observation On Treatment Of TypeⅢA Chronic Prostatitis (Kidney Deficiency,Dampness And Heat Type) Patients With Jiawei BiTu Soup

Objective: To observe the clinical efficacy of Jiawei Bi Tu Soup in the treatment of type ⅢA chronic prostatitis(kidney deficiency damp-heat type),and to analyze its influence on the serum pro-inflammatory cytokines IL-8and TNF-α to explore the treatment of CP with Jiawei Bi Tu Soup The possible mechanism of TCM provides a certain basis for the treatment of chronic prostatitis(CP)with traditional Chinese medicine.Methods: The patients with type IIIA prostatitis(kidney-deficiency damp-heat type)who were treated in the Andrology Clinic of Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine from April 2020 to January 2021 were numbered according to the order in which they visited,and were divided into the control group and the treatment group using a random number table 40 cases.The control group was treated with oral levofloxacin lactate dispersible tablets and tamsulosin hydrochloride sustained-release tablets;the treatment group was treated with traditional Chinese medicine Jiawei Bi Tu Soup on the basis of the control group,and both groups were treated with 28/d as a course of treatment.The chronic prostatitis symptom index score(NIH-CPSI),TCM syndrome score,the routine white blood cell count level of the prostate fluid,and the serum interleukin 8(IL-8)and tumor necrosis factor alpha(TNF-α)were compared between the two groups of patients before and after treatment.α)expression level,and evaluate the efficacy.The data were analyzed using SPSS25.0statistical software.Results: 1.Before treatment,there was no significant difference between the two groups of patients in age,disease course,NIH-CPSI score,TCM syndrome score,white blood cell and serum TNF-a,IL-8 levels and levels in routine prostatic fluid(P>0.05).2.In this clinical study,a total of 76 patients completed the clinical observation,of which 38 were completed in the control group,1 cured,15 markedly effective,14 effective,and 8 ineffective.The total effective rate was 78.94%;the treatment group completed 38 people,5were cured,21 were markedly effective,8 were effective,and 4 were ineffective.The total effective rate was 89.47%.The difference between the two groups was statistically significant(P<0.05),indicating that the treatment of type Ⅲ A prostatitis(Kidney Deficiency Damp-heat Syndrome))In the clinical efficacy of patients,the treatment group is better than the control group.3.After treatment,the two groups(NIH-CPSI)and TCM syndrome scores were significantly lower than before treatment,the difference was significant(P<0.01),and the treatment group was effective in improving NIHCPSI and TCM syndrome scores It is better than the control group,and the difference is statistically significant(P<0.05),indicating that the traditional Chinese medicine Jiawei Bi Tu Soup can improve the clinical symptoms of patients and improve the quality of life of patients.4.After treatment,there was no statistically significant difference between the number of white blood cell counts between the treatment group and the control group(P>0.05),indicating that the control group and the treatment group had the same effect in reducing the white blood cell count of the prostate fluid.5.Both the two groups can significantly reduce the serum TNF-αand IL-8 levels of patients in the treatment of type IIIA prostatitis(kidney deficiency damp-heat syndrome),and the difference is significant(P <0.01);and the above indicators are after treatment Compared with the groups,the difference was statistically significant(P <0.05),indicating that the use of Chinese medicine Jiawei Bi Tu Soup is beneficial to alleviate the inflammatory response in patients with type ⅢA prostatitis.Conclusions: 1.Chinese medicine Jiawei Bi Tu Soup can significantly reduce the TCM syndrome score and prostate symptom index of patients with type ⅢA prostatitis.Therefore,the traditional Chinese medicine Jiawei Bi Tu Soup can better improve the clinical symptoms of patients with type IIIA prostatitis and improve the quality of life of patients,and it is worthy of clinical inheritance and popularization.2.Chinese medicine Jiawei Bi Tu Soup can reduce the serum levels of pro-inflammatory cytokines IL-8 and TNF-αin patients with type ⅢA prostatitis.3.In the treatment of type ⅢA prostatitis,the traditional Chinese medicine Jiawei Bi Tu Soup reduces the body’s overall inflammatory response may be one of its therapeutic mechanisms.