Clinical Study On Tiaoqi Xiaopi Decoction In The Treatment Of Functional Dyspepsia Postprandial Discomfort Syndrome(Liver Stomach Disharmony Syndrome)

Objective:In this paper,we used the self-made "Tiaoqi Xiaopi decoction" to treat functional dyspepsia postprandial discomfort syndrome(liver-stomach disharmony syndrome),and compared it with Chinese Patent Medicine "Weisu Granule" to analyze the clinical efficacy and safety of Tiaoqi Xiaopi decoction,open up a new way for the treatment of this disease in the future.Methods:110 outpatients of Shanxi Traditional Chinese Medicine Hospital were divided into treatment group(55 cases)and Control Group(55 cases)according to the 1:1distribution standard.After basic treatment,the treatment group was treated with Tiaoqi Xiaopi decoction and the control group was treated with Weisu Granule.The time of treatment was 4 weeks.The total score of TCM and Western medicine symptom,the distribution of single symptom,the threshold of stomach and the intake of satiety were counted before and after treatment.Results SPSS25 was used.O Software to analyze data.Results:After treatment,the two groups of patients in TCM syndrome curative effect,the overall curative effect of Western medicine were significantly improved.After treatment,the total effective rates of the treatment group and the control group were 90.2%and 72.0% respectively,P<0.05 by rank sum test,so Tiaoqi Xiaopi decoction was better than Weisu granule in relieving the overall symptoms of traditional Chinese medicine;after treatment,the total effective rates of the treatment group and the control group were 88.2%and 70.0% respectively,P<0.05 by rank sum test,Therefore,Tiaoqi Xiaopi decoction is better than Weisu granule in improving clinical symptoms.After treatment,the symptom scores of the treatment group were significantly reduced(P<0.01),while in the control group,except nausea and vomiting,dry mouth and bitter mouth(P>0.05),the other scores were significantly reduced(P<0.01).Comparison between groups,the symptoms of TCM syndrome such as epigastric distension,fullness and pain of flanks,good Taixi,irritability,belching,dry mouth,bitter mouth,nausea and vomiting were all P<0.05,which indicated that there were differences in disease distribution between the two groups after treatment.Therefore,Tiaoqi Xiaopi decoction was better than Weisu granule in relieving the above symptoms;in heartburn and acid regurgitation,the results were all P>0.05,Therefore,Tiaoqi Xiaopi Decoction and Weisu granule have the same effect in relieving the above symptoms.The overall efficacy of Western medicine in postprandial fullness and early satiety were both P<0.05,indicating that there was a difference in the distribution of disease between the two groups after treatment,indicating that Tiaoqi Xiaopi decoction was better than Weisu granule in relieving the above symptoms.There was no significant difference in the distribution of the above symptoms between the two groups after treatment.Tiaoqi Xiaopi decoction had the same effect as Weisu granule.After the treatment of liquid nutrition meal load test,there were all P<0.05,indicating that there were significant differences in the threshold and the amount of full drink between the two groups after treatment.Therefore,compared with Weisu granule,Tiaoqi Xiaopi decoction has obvious advantages in improving gastric receptivity and intragastric sensitivity.Conclusion:Tiaoqi Xiaopi decoction is more effective than Weisu granule in the treatment of postprandial discomfort syndrome(disharmony between liver and stomach),and it is safe and reliable in clinical application.