The Chief Physician Jiang Chunzhuang’s The Conclusions Of Treating NSCLC Which Are The TCM Syndrome Distribution Law And Clinical Medication Experience

Objective: This study prodives the important clinical application value for judging TCM classification and using medicine of NSCLC by analyzing chief physician Jiang Chunzhuang’s the conclusions of treating NSCLC retrospectively which are the TCM syndrome distribution law and clinical medication experience.Methods: With the method of retrospective studies,collecting WEIHAI Hospital of Traditional Chinese Medicine’s clinical cases of NSCLC which were diagnosed through pathology and cytology.These cases belong to oncology utpatient and inpatient department.Filling in the questionnaire of NSCLC’s Clinical Study Cases.According the questionnaire,studing the TCM syndrome distribution of the patient’s general condition(including gender,age,pathological stage,pathological classification,KPS score),simple surgical treatment,non-operative treatment(including radiotherapy,chemotherapy,targeted therapy)separately and analyzing these distribution law with statistical software.Applicating TCM auxiliary system to establish diagnosis and treatment database about clinical medicine usage regulation.Summarizing chief physician Jiang Chunzhuang’s clinical medication experience by the methods of association rule analysis and descriptive analysis.Results: 1.Syndrome distribution: The gender,age and pathological classification of patients can not effect the TCM syndrome distribution,but pathological stage and KPS score can make an impact.After simple surgical treatment,the main performance of patients with non-small cell lung cancer is lung-spleen Qi deficiency syndrome,while the other syndrome types are rare.Comparing with simple surgical treatment,the proportion of lung-spleen qi deficiency syndrome decreased but other syndrome types increased in patients treated by non operative method.The chemotherapy patients exhibite largely lung-spleen Qi deficiency syndrome and deficiency of Qi and Yin.After treatment with targeted therapy,patients are often manifested with syndrome of Yin deficiency and toxicity and deficiency of Qi and Yin.2.255 kinds of drugs are involved in 195 prescriptions,and the top 10 most common drugs are astragalus membranaceus,atractylodes,scrophulariae,peoria cocos,radix scutellariae,mulberry leaf,chrysanthemum indicum,radix ophiopogonis,cortex mori radicis,radix platycodi.There are two kinds of drug properties: four characters and five tastes.The four characters means cold drugs are the main ones followed by warm drugs and the usage of heat-clearing drugs is high.Through the method of association rules,common drugs are obtained: astragalus membranaceus,peoria cocos,atractylodes.Conclusion: 1.Syndrome distribution law: The distribution of syndrome types is different between the patients treated with surgery alone and those treated with non-surgery.The symptoms of the patients treated by surgery are mostly mild,early stage,and lung-spleen Qi deficiency syndrome mainly.Nevertheless,the pathogensis of patients treated by non-surgery is more complex.The symptoms often appear to be deficiency in origin and enrichment in symptom.Deficiency syndrome is mostly manifested as Qi deficiency,Yin deficiency and deficiency of Qi and Yin.The main performance of real syndrome is phlegm,heat and silt interlock in the chest,and it’s symptoms are variable relatively,symptoms are complex as well.2.Summarizes of medication experience: The tutor always pay attention to protect spleen and stomach,individual therapy,improve healthy Qi,support the healthy Qi to dispel evil spirit.