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Distribution And Prognosis Of Syndromes Of 98 Cases Of Non - Small Cell Lung Cancer

Posted on:2016-12-09Degree:MasterType:Thesis
Country:ChinaCandidate:Z ChaiFull Text:PDF
GTID:2134330461492880Subject:General medicine
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Lung cancer, the primary bronchogenic carcinoma, is originated in the bronchial mucosa and (or) gland malignant tumors. Which accounts for about 80% to 90% of patients with lung cancer belongs to non-small cell lung cancer. At present, the world health organization has cancer is defined as controllable chronic disease. Lung cancer, as one of the chronic diseases, which may increase painless, often seriously affects the patient’s ability to work and life quality, and cost of treatment is expensive, increase the economic burden of the society, family, so it is particularly important to slow disease management for lung cancer. Lung cancer increases with smoking, environmental pollution, urban industrialization, an aging population, rural urbanization, and way of life is bad. Along with the increasing morbidity, mortality, the lung cancer has become a serious threat to human life and health of malignant tumor. Through all kinds of way the disease the 5-year survival rate after treatment are still less than 15%. So, control the incidence of lung cancer has now become a hot issue concerned by the world. The prognosis of patients with lung cancer can generally from age, gender, pathological type and pathological staging several aspects, such as predicted. Under the above background, the research of TCM syndrome type and whether there is a correlation between influence factors are discussed, in order to improve the understanding of TCM syndrome type of lung cancer, and improve the prognosis of disease.By the method of retrospective analysis, the Beijing university of Chinese medicine in the third affiliated hospital of tumor onset in October 2012 to March 2015 non-small cell lung cancer patients admitted during the period of study, a total of 98 cases. For the patient’s name, gender, age, clinical signs, diagnosis and transfer of information analysis, and the results are discussed.Retrospective analysis of 98 cases of patients with non-small cell lung cancer, male 55 cases (56.12%) and 43 cases (43.88%), female sex ratio is about:1.279:1. Age between 29-90, average age 66.81±12.50, the median age of 67.50 years old, Of men with an average age of 69.05±12.27 years of age, female and the average age of 63.93±12.35 years, main onset ages of 50-90 years, accounted for 92.9%, including 60-79 years for the peak age of the disease. Of traditional Chinese medicine in the form than the order from high to low is:qi and Yin deficiency type 38 people,38.8% of the total. Lung collaterals blood stasis resistance type 34 people,34.7%of the total; Phlegmy wet aggregates type lung 17 people,17.3% of the total. Yin poison narcissistic 9 people,9.2% of the total. By chi-square test, X2= 30.966, P= 0.000. was statistically significant, that differences between TCM syndrome type in non-small cell lung cancer. Gender distribution among different syndrome types suggests men were slightly more than female patients. By chi-square test, X2= 0.340, P= 0.952, no statistical significance, shows no obvious difference between TCM syndrome type and gender. Statistics of 98 patients with non-small cell lung cancer pathology diagnosis, due to the large cell carcinoma, alveolar theoretical frequency is too small, so the only calculated adenocarcinoma and squamous cell carcinomas, The chi-square test, X2= 0.549, P= 0.947, no statistical significance, TCM syndrome type and no significant difference between adenocarcinoma and squamous cell carcinomas. Tumor metastasis is statistical analysis transfer by chi-square test, X2= 4.295, P= 0.906, show no significant differences between TCM syndrome type and tumor metastasis. Analysis of complications, the chi-square, X2= 1.477, P= 0.715, no statistical significance, obstructive pneumonia, pleural effusion in no difference between the distribution of TCM syndrome types. Statistical patients clinical symptoms integral in the TCM syndrome type distribution, and examined the Kruskal Wallis H-and X2= 10.853, P= 0.013, was statistically significant, indicated that clinical symptoms integral in the TCM syndrome type distribution differences,Analysis of traditional Chinese medicine and integral value, the relationship between qi and Yin deficiency, lung collaterals blood stasis resistance highest proportion of heavy symptoms in two groups of patients, the clinical symptoms of more serious, its prognosis is poorer. Cassette score is more than 70 points and 16 cases,16.3% of the total, carr’s score is between 40-50 cases between 70 and 51.0% of the total, carr’s score 40 points less than or equal to 32 cases,32.7% of the total.Comparison lung collaterals and blood stasis type resistance in patients with grade has the greatest number less than or equal to 40 points, the worse condition.Checked by Kruskal Wallis H-, X2= 8.882, P= 0.031, there is statistical significance, shows that cassette score distribution differences in TCM syndrome types.Further by Wilcoxon rank and inspection, found that lung collaterals blood stasis and Yin poison narcissistic, blocking lung collaterals blood stasis and phlegm blocking type lung cartesian score differences between wet aggregates.Lung collaterals in patients with blood stasis type resistance KPS 40 constitute or less than the highest, suggests the 1 type condition, a poor prognosis.1. The differences between TCM syndrome type in non-small cell lung cancer. The lung collaterals blood stasis resistance and gas Yin deficiency of prevalence rate is higher, and the number of cases both were significantly higher than the Yin deficiency, phlegmy wet aggregates lung; Qi and Yin deficiency type and no obvious difference between lung collaterals blood stasis resistance type, Yin poison narcissistic and phlegmy wet aggregates have no obvious difference between lung type.2. Adenocarcinoma and squamous cell carcinomas in no obvious difference between different syndrome types.3. The doctor of traditional Chinese medicine syndrome and no obvious difference between tumor and complications.4. Clinical symptoms integral in the TCM syndrome type distribution differences, two among the qi and Yin deficiency, lung collaterals two groups of clinical symptoms, blood stasis resistance and poor prognosis.5. Cassette score distribution differences in TCM syndrome types, including lung collaterals blood stasis resistance type patients is heavier, a poor prognosis.
Keywords/Search Tags:non-small cell lung cancer, The prognosis, The doctor of traditional Chinese medicine syndrome
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