A Preliminary Study On The Effect Of Yiqitongmai Prescription On The Quality Of Life Of Patients With Coronary Heartdisease(Qi Deficiency And Blood Stasis)after PCI

Objective:To preliminarily explore the the rapeu tic effect of yiqitongmai prescription on the quali ty of life of patients with qi-deficiency and blood stasis after PCI of coronary heart disease,mainly including the effect on clinical symptoms,examination results and safety,and provide some clinical basis for future research on the treatment of patients with PCI by tradi tional Chinese medicine.Methods:It was collected from November 2018 and lasted for one year.Sixty-five outpatients and inpatients in the department of heart disease of yantai hospital of traditional Chinese medicine affiliated hospital of shandong university of Chinese medicine that met the inclusion criteria and exclusion criteria were qualified subjects.They were randomly divided into control group and treatment group according to the simple randomization method.In the control group,conventional western medicine after PCI was taken orally alone,and corresponding hypoglycemic drugs and antihypertensive drugs were taken orally for patients with hypertension and diabetes.The treatment group was treated in the same way as the control group,and the decoction yiqi tongmai was added and subtracted for 3 months.At the end of 3 months,the therapeutic effect and safety indexes of the two groups were observed.The following items were observed:Seattle angina scale(SAQ),health status questionnaire(sf-12),TCM syndrome score,6min walking test,electrocardiogram;And whether liver function(ALT,AST),kidney function(BUN,Cr)and blood routine were abnormal before and after treatment.Result:SPSS23.0 statistical analysis showed that there was no significant difference between the two groups(P>.05).Survival quality,the tr eatment group SF-12 each dimension score were higher than the control group,and in the"function","vigor","physiological function","social function" is better than that in control group(P<0.05),and two groups of "overall health","body pain","emotional functions","mental health" score had no obvious difference(P>0.05);SAQ score:after 3 months,the treatment group had better efficacy in "degree of physical activity limitation","degree of treatment satisfaction","stable state of angina pectoris" and "angina pectoris attack" than the control group(P<0.05),but there was no significant difference in "degree of disease cognition" between the two groups(P>0.05).In terms of TCM symptom scores,after 3 months of systematic treatment,the symptom scores of both groups were reduced,but compared with the control group,the scores of the treatment group were significantly reduced,and the clinical discomfort was significantly improved(P<0.05).In the 6-min walking experiment,the walking distance of the two groups was prolonged to different degrees(P<0.05),and the treatment group was better than the control group(P<0.05).In terms of ecg,the effective rate after treatment was 16.1 in the control group and 29 in the treatment group,and there was no significant difference in the improvement of ecg between the two groups(P>,0.05).Before and after treatment,no adverse reactions occurred in the two groups of subjects,and there were no abnormal test indicators.Conclusion:The addition and subtraction of yiqitongmai prescription can improve the quality of life of patients with qi-deficiency and blood-stasis after PCI,and the safety is more reliable.