Comparison Of Drug Coated Balloon And Common Balloon In The Treatment Of Autogenous Arteriovenous Fistula Stenosis

Objective To compare the efficacy of drug coated balloon and common balloon in autogenous arteriovenous fistula stenosis.Method A total of 42 patients with autogenous arteriovenous fistula stenosis admitted to the Third Affiliated Hospital of Bengbu Medical College from February 2019 to February 2020 were selected as the study subjects.According to the treatment methods,the patients were divided into drug coated balloon（DCB）group（n=20）and common balloon（CB）group（n=22）.Patients in DCB group treated with paclitaxel release high pressure shunt balloon dilatation,and patients in CB group treated with common balloon dilatation.The success rate of operation,stenosis diameter and hemodialysis blood flow before and after operation,the primary patency rate of arteriovenous fistula at 1,6 and 12 months after operation and complications within one month after operation were compared between the two groups.Results The success rate of operation was 100% in both groups.Before operation,the diameter of stenosis and dialysis blood flow of DCB group were（1.4±0.3）mm and（124.8±16.0）m L/min,respectively,compared with（1.3±0.4）mm and（119.1±15.3）m L/min of CB group,there was no statistical significance（P>0.05）;after operation,the diameter of stenosis and dialysis blood flow of DCB group were（3.4±0.5）mm and（258.0±14.7）m L/min,respectively,compared with（3.2±0.4）mm and（251.6±8.9）m L/min of CB group,there was no statistical significance（P>0.05）.The diameter of stenosis and dialysis blood flow after operation were significantly improved compared with those before operation in the two groups（P<0.01）.At 1 month after operation,there was no significant difference in the primary patency rate of arteriovenous fistula between DCB group and CB group（100% vs 90.9%;P>0.05）.At 6 months after operation,the primary patency rate in DCB group was significantly higher than that in CB group,and the difference was statistically significant（85.0% vs 54.5%;P<0.05）.At 12 months after operation,there was no significant difference in the primary patency rate between the two groups（70% vs 45.5%;P>0.05）,and there was no statistical significance in the incidence of complications in one month after operation between the two groups（P>0.05）.Conclusion Drug coated balloon angioplasty is superior to common balloon angioplasty in the treatment of autogenous arteriovenous fistula stenosis,which can be used as one of the safe and effective options for the treatment of autogenous arteriovenous fistula stenosis.