Objective:1.To evaluate the efficacy and safety of the combined therapy of triamcinolone acetonide,CO2 lattice laser and Optimal Pulsed Technology(OPT)in the treatment of hypertrophic scars.2.To provide a reference for the selection of combined therapy for hypertrophic scars.Method:63 cases of hypertrophic scar patients who were admitted to the medical cosmetology department of the Second Affiliated Hospital of Guangxi Medical University from August 2017 to June 2019 were selected as the subjects.The combined therapy of triamcinolone acetonide,CO2 lattice laser and OPT was used for treatment.By analyzing the changes of Vancouver Scar Scale(VSS)scores before and after treatment,the occurrence of adverse reactions(such as tissue atrophy,infection,necrosis,pigmentation,hypopigmentation,telangiectasia,etc.),the improvement of symptoms(such as pain,pruritus)and the satisfaction of patients,the effectiveness and safety of the combined therapy were evaluated.Result:1.The VSS score of the patients before treatment was(10.03+1.83),while it was(6.46+1.63)after treatment.The difference was statistically significant(t=19.470,P<0.001).2.After treatment,the percentages of patients who were cured,markedly effective,effective and ineffective were 9.5%(6 cases),60.3%(38 cases),27%(17 cases)and 3.2%(2 cases),respectively.The total efficiency rate was 96.8%(61 cases).3.The percentages of patients whose symptoms of pain improved was93.3%(14/15),and whose symptoms of pruritus improved was 88.9%(16/18).4.The occurrence of adverse reactions:in all cases,pigmentation occurred in 3 cases(4.8%),of which 2 cases occurred in about 1 month after the treatment of CO2 lattice laser,1 case occurred in about 20 days after the use of triamcinolone acetonide,continued the original treatment without additional intervention,and then improved itself.Tissue atrophy occurred in 1 case(1.6%),which was gradually evident in 2 weeks after the injection of triamcinolone acetonide.Continued the original treatment without additional treatment,no obvious improvement.No more adverse reactions such as hypopigmentation,ulceration,infection,telangiectasia occurred.5.Patients’satisfaction:the percentages of patients who were satisfied,less satisfied and dissatisfied were 66.7%(42 cases),30.2%(18 cases)and 4.8%(3cases),respectively.Conclusion:The combined therapy of triamcinolone acetonide,CO2 lattice laser and OPT can significantly reduce the patients’VSS score,significantly improve the symptoms of pain and pruritus.With few and light adverse reactions,generally without special intervention,its efficiency and patients’satisfaction is high.The combined therapy of triamcinolone acetonide,CO2 lattice laser and OPT is safe and effective in the treatment of hypertrophic scars. |